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Inhibition of TrkC phosphorylation in mouse BaF3 cells expressing TEL fused TrkC G623R mutant incubated for 6 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Drug uptake in mouse NIH/3T3 cells expressing TrkC receptor assessed as TrkC receptor-mediated compound localization in mitochondrial after 30 mins by Mito-tracker dye based fluorescence microscopy analysis
Assay data:1 Active, 2 Tested
Drug uptake in mouse NIH/3T3 cells expressing TrkC receptor assessed as TrkC receptor-mediated compound localization in lysosome after 30 mins by Lyso-tracker dye based fluorescence microscopy analysis
Drug uptake in mouse 4T1 cells expressing TrkC receptor assessed as TrkC receptor-mediated compound localization in lysosome after 30 mins by Lyso-tracker dye based fluorescence microscopy analysis
Survival of TrkC receptor transfected NIH3T3 cells at 50 uM with 100 pM NT-3
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Survival of TrkC receptor transfected NIH3T3 cells at 50 uM without NT-3
Survival of TrkC receptor transfected NIH3T3 cells at 2 uM with 100 pM NT-3
Survival of TrkC receptor transfected NIH3T3 cells at 2 uM without NT-3
Survival of TrkC receptor transfected NIH3T3 cells at 10 uM with 100 pM NT-3
Survival of TrkC receptor transfected NIH3T3 cells at 10 uM without NT-3
Survival of TrkC receptor transfected NIH3T3 cells at o.4 uM with 100 pM NT-3
Survival of TrkC receptor transfected NIH3T3 cells at o.4 uM without NT-3
Survival of TrkC receptor transfected NIH3T3 cells with 2000 pM NT-3 (positive control)
Survival of TrkC receptor transfected NIH3T3 cells with suboptimal NT-3 (100 pM)
Survival of TrkC receptor transfected NIH3T3 cells without NT-3 (negative control)
Binding of FITCanti-TrkC-Ab to TrkC receptor transfected NIH3T3 cells (positive control)
Binding affinity for TrkC receptor transfected cells at 20 uM without NT-3
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