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Agonist activity at NY4 receptor in mouse descending colon mucosa assessed as increase in mucosal antisecretory response at 30 uM incubated for 5 mins
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Positive allosteric modulation of NY4 receptor in mouse descending colon mucosa assessed as increase in mucosal antisecretory response to pancreatic polypeptide at 30 uM preincubated for 5 mins followed by pancreatic polypeptide addition after 20 mins
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of [125I]-PYY(1 to 36 residues) from mouse Y4R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Mouse Y4 receptor (Neuropeptide Y receptors)
Assay data:7 Active, 7 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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