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Mouse DP1 receptor (Prostanoid receptors)
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after 10 mins by enzyme immunoassay
Assay data:29 Active, 2 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 31 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Displacement of [3H]-PGD2 from mouse DP receptor expressed in CHO cells after 20 mins by liquid scintillation counting
Assay data:13 Active, 12 Activity ≤ 1 µM, 20 Tested
Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production
Assay data:19 Active, 19 Activity ≤ 1 µM, 24 Tested
Displacement of [3H]PGD2 from mouse prostanoid DP receptor expressed in CHO cells after 60 mins by liquid scintillation counting
Assay data:24 Active, 23 Activity ≤ 1 µM, 24 Tested
Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immunoassay in the presence of 0.1% BSA
Assay data:22 Active, 1 Activity ≤ 1 nM, 22 Activity ≤ 1 µM, 31 Tested
Assay data:26 Active, 26 Activity ≤ 1 µM, 31 Tested
Inhibition of mouse DP receptor
Assay data:1 Active, 1 Tested
Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 receptor; NT denotes not tested
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 receptor
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
Inhibition of mouse Prostanoid DP receptor; NT not tested
Assay data:2 Tested
Inhibition of mouse Prostanoid DP receptor; Not tested
Inhibition of mouse Prostanoid DP receptor
Assay data:8 Active, 2 Activity ≤ 1 µM, 10 Tested
Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptor
Assay data:14 Active, 14 Activity ≤ 1 µM, 14 Tested
Binding affinity for mouse Prostanoid DP receptor
Assay data:11 Active, 8 Activity ≤ 1 µM, 13 Tested
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