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Inhibition of mouse liver microsome SCD assessed as reduction in [3H]H2O production using stearoyl [9,10-3H]CoA as substrate in presence of NADH incubated for 30 mins by scintillation counting method
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of SCD1 in CD1 mouse liver at 3 uM using stearoyl [9,10-3H] CoA as substrate and NADPH incubated for 2 hrs by scintillation counting method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of SCD1 in CD1 mouse liver at 100 nM using stearoyl [9,10-3H] CoA as substrate and NADPH incubated for 2 hrs by scintillation counting method
Assay data:8 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water after 20 hrs by scintillation counting analysis
Assay data:28 Active, 26 Activity ≤ 1 µM, 29 Tested
Inhibition of SCD1 in mouse liver microsomes
Assay data:25 Active, 23 Activity ≤ 1 µM, 27 Tested
Assay data:27 Active, 24 Activity ≤ 1 µM, 28 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Assay data:48 Active, 45 Activity ≤ 1 µM, 57 Tested
Inhibition of mouse SCD1
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of mouse SCD-1
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of mouse liver microsome SCD1
Assay data:7 Active, 8 Activity ≤ 1 µM, 11 Tested
Inhibition of SCD1 in mouse microsome assessed as reduction in conversion of [14C]stearic acid to [14C]oleic acid after 30 mins
Assay data:9 Active, 4 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested
Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 mins
Assay data:20 Active, 20 Activity ≤ 1 µM, 20 Tested
Inhibition of SCD1 in mouse microsomal liver S9 microsomal fraction assessed as conversion of [14C]stearate to [14C]oleate after 60 mins
Assay data:23 Active, 4 Activity ≤ 1 nM, 24 Activity ≤ 1 µM, 28 Tested
Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 mins
Assay data:22 Active, 7 Activity ≤ 1 nM, 19 Activity ≤ 1 µM, 29 Tested
Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleate
Assay data:16 Active, 2 Activity ≤ 1 nM, 18 Activity ≤ 1 µM, 20 Tested
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