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Mouse TRH1 receptor (Thyrotropin-releasing hormone receptors)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cell membranes at 30 uM after 4 hrs by scintillation counting method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Displacement of [2,5-125I2]-Me-His-TRH from wild type TRHR mouse brain membranes at 0.3 uM after 4 hrs by scintillation counting method
Displacement of [2,5-125I2]-Me-His-TRH from wild type TRHR mouse brain membranes at 1 uM after 4 hrs by scintillation counting method
Displacement of [2,5-125I2]-Me-His-TRH from wild type TRHR mouse brain membranes at 3 uM after 4 hrs by scintillation counting method
Displacement of [2,5-125I2]-Me-His-TRH from wild type TRHR mouse brain membranes at 10 uM after 4 hrs by scintillation counting method
Displacement of [2,5-125I2]-Me-His-TRH from wild type TRHR mouse brain membranes at 30 uM after 4 hrs by scintillation counting method
Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membrane at 3 uM after 4 hrs by scintillation counting method
Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membrane at 30 uM after 4 hrs by scintillation counting method
Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membranes at 0.01 uM after 4 hrs by scintillation counting method
Assay data:2 Tested
Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membranes at 0.1 uM after 4 hrs by scintillation counting method
Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membranes at 1 uM after 4 hrs by scintillation counting method
Displacement of [3H]-Me-His-TRH from wild type TRHR mouse brain membranes at 10 uM after 4 hrs by scintillation counting method
Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as IP1 formation after 1 hr by ELISA
Assay data:10 Active, 9 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as Ca2+ release by FLIPR assay
Assay data:13 Active, 1 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 16 Tested
Displacement of [3H]-Me-His-TRH from mouse TRH-R1 expressed in HEK293 cells preincubated for 15 mins measured after 4 hrs
Assay data:4 Active, 3 Activity ≤ 1 µM, 16 Tested
Agonist activity at mouse TRH-R1 expressed in HEK293 cells assessed as induction of changes in intracellular Ca2+ level by FLIPR method
Assay data:16 Active, 1 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 18 Tested
Displacement of [3H]-1-MeHis-TRH from mouse TRH-R1 expressed in HEK293 cells incubated up to 4 hrs by scintillation counting method
Assay data:1 Active, 1 Activity ≤ 1 µM, 18 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Secondary screen NFkB readout
Assay data:1483 Active, 3847 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
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