BioAssay by Target (List) for Gene (Select 22848) - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

Items: 1 to 20 of 176

<< First< Prev

Page of 9

Select item 19628941.

AAK1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Tested

AID:: 1962894

Summary Related BioAssays by Target

Select item 19627902.

AAK1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Tested

AID:: 1962790

Summary Related BioAssays by Target

Select item 19626773.

AAK1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Tested

AID:: 1962677

Summary Related BioAssays by Target

Select item 19625784.

AAK1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Tested

AID:: 1962578

Summary Related BioAssays by Target

Select item 19483325.

Inhibition of AAK1 (unknown origin)

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1948332

Summary Related BioAssays by Target

Select item 19142366.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000165b AAK1

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914236

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19132117.

Affinity Biochemical interaction (Competition binding assay) EUB0000166b AAK1

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Active, 1 Tested

AID:: 1913211

Summary Compounds, Active Related BioAssays by Target

Select item 19132098.

Affinity Biochemical interaction (TR-FRET binding-displacement assays) EUB0000165b AAK1

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913209

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19129549.

Affinity On-target Cellular interaction (NanoBRET assay (HEK293T cells)) EUB0000165b AAK1

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912954

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191249610.

Thermal Shift Assay. Domain: start/stop: T27-A365

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:27 Tested

AID:: 1912496

Summary Related BioAssays by Target

Select item 191101211.

Binding affinity to AAK1 (unknown origin) assessed as change in melting temperature at 10 uM by SYPRO orange dye based DSF assay

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Tested

AID:: 1911012

Summary PubMed Citation Related BioAssays by Target

Select item 190457112.

Inhibition of full length human AAK1 expressed in HEK293F cells assessed as suppression of AP2 phosphorylation measured after 3 hrs by Western blot analysis based cellular assay

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:39 Active, 15 Activity ≤ 1 nM, 39 Activity ≤ 1 µM, 39 Tested

AID:: 1904571

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190456913.

Inhibition of bacterially expressed GST-Xa-tagged human AAK1 using 5-FAM-labelled Aha-KEEQSQITSQVTGQIGWR-NH2 peptide as substrate incubated for 3 hrs in presence of ATP by electrophoretic analysis

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:55 Active, 27 Activity ≤ 1 nM, 55 Activity ≤ 1 µM, 55 Tested

AID:: 1904569

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190259514.

Binding affinity to AAK1 (unknown origin)

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1902595

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190259415.

Inhibition of AAK1 (unknown origin)

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1902594

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190257016.

Inhibition of human wild type partial length AAK1 (G25 to L333 residues) expressed in bacterial expression system assessed as remaining activity at 1 uM relative to control

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:1 Tested

AID:: 1902570

Summary PubMed Citation Related BioAssays by Target

Select item 190255817.

Inhibition of full length human AAK1 expressed in HEK293F incubated for 3 hrs by Western blot analysis

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested

AID:: 1902558

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190255518.

Inhibition of recombinant human GST-Xa-tagged-AAK1 (30 to 330 residues) expressed in baculovirus expression system using (5 -FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated for 3 hrs in presence of ATP by electrophoretic analysis

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1902555

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190255419.

Inhibition of recombinant human GST-Xa-tagged-AAK1 (30 to 330 residues) using (5-FAM)-Aha-KEEQSQITSQVTGQIGWR-NH2 as substrate incubated for 3 hrs in presence of ATP by electrophoretic analysis

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:31 Active, 28 Activity ≤ 1 µM, 31 Tested

AID:: 1902554

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 190056520.

Inhibition of AAK1 (unknown origin) at 0.1 uM relative to control

Source:: ChEMBL

Protein Target:: AP2-associated protein kinase 1

Assay data:2 Tested

AID:: 1900565

Summary PubMed Citation Related BioAssays by Target

<< First< Prev

Page of 9

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (2)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (62)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (18)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (53)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (59)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (41)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (130)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (46)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (105)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (68)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Recent activity

Clear Turn Off Turn On

BioAssay by Target (List) for Gene (Select 22848) (176)
PubChem BioAssay

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay