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Rat Y5 receptor (Neuropeptide Y receptors)
Assay data:21 Active, 21 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at rat NPY Y5 receptor
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antagonist activity at rat NPY5 receptor
Inhibition of rat Y5 receptor
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
Displacement of [125I]PYY from rat NPY Y5 receptor
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Antagonist activity at rat NPY Y5 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production
Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of PYY effect on forskolin-stimulated cyclic AMP formation in C6 cells expressing rat NPY Y5 receptor; n.d. denotes ''not determined
Assay data:15 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of PYY effect on forskolin-stimulated cyclic AMP formation in C6 cells expressing rat NPY Y5 receptor
Assay data:27 Tested
Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cells
Assay data:30 Active, 42 Activity ≤ 1 µM, 42 Tested
In vitro binding affinity against rat neuropeptide Y5 receptor; ND means Not determined
Assay data:2 Tested
In vitro binding affinity against rat neuropeptide Y5 receptor
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Functional response of NPY to inhibit forskolin-stimulated cAMP in cells stably transfected with rat Neuropeptide Y receptor type 5
Binding affinity to the rat Neuropeptide Y receptor type 5 was determined using [125I]- [Leu31,Pro34]PYY as radioligand
The compound was tested for the binding affinity against Neuropeptide Y receptor type 5 in rat
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Compound was tested for rat Neuropeptide Y receptor type 5
Binding affinity against rat Neuropeptide Y receptor Y5
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