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Selectivity interaction (AlphaScreen assay) EUB0000214b L3MBTL
Assay data:1 Active, 1 Tested
SummaryRelated BioAssays by Target
AlphaScreen Assay from Article 10.1021/cb500956g: "Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1."
Assay data:25 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of L3MBTL1 (unknown origin) by fluorescence polarization assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of L3MBTL1 (unknown origin) by AlphaScreen assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Inhibition of GST-fused L3MBTL1 3xMBT-D355N mutant (unknown origin)/biotinylated H4K20Me1 peptide interaction at 5 to 25 uM by pull down assay based western blot analysis
Assay data:2 Tested
Inhibition of GST-fused L3MBTL1 3xMBT domain (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells/biotinylated H4K20Me1 peptide interaction assessed as binding of L3MBT1 repeats to H4K20Me1 at 25 uM by pull-down assay based western blot analysis
Assay data:3 Tested
Inhibition of GST-fused L3MBTL1 3xMBT domain (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells/biotinylated H4K20Me1 peptide interaction assessed as binding of L3MBT1 repeats to H4K20Me1 at 5 uM by pull-down assay based western blot analysis
Inhibition of GST-fused L3MBTL1 3xMBT domain (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells/biotinylated H4K20Me1 peptide interaction assessed as binding of L3MBT1 repeats to H4K20Me1 at 1 uM by pull-down assay based western blot analysis
Inhibition of GST-fused L3MBTL1 3xMBT domain (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells/biotinylated H4K20Me1 peptide interaction assessed as binding of L3MBT1 repeats to H4K20Me1 by pull-down assay based western blot analysis
Antagonist activity at N-terminal His6-tagged L3MBTL1 (unknown origin) expressed in Escherichia coli BL21 Codon Plus RIL cells assessed as inhibition of L3MBTL1/biotinylated H4K20Me1 peptide interaction at 30 uM after 30 mins by AlphaScreen assay
Assay data:14 Tested
Antagonist activity at N-terminal His6-tagged L3MBTL1 (unknown origin) expressed in Escherichia coli BL21 Codon Plus RIL cells assessed as inhibition of L3MBTL1/biotinylated H4K20Me1 peptide interaction after 30 mins by AlphaScreen assay
Assay data:3 Active, 24 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Binding affinity to L3MBTL1 (unknown origin) by isothermal titration calorimetry
Assay data:2 Active, 4 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Inhibition of His-tagged L3MBTL1 (unknown origin) using H4K20Me1 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay
Assay data:2 Active, 25 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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