Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of GOT1 (unknown origin)
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of C-terminal His6-tagged human recombinant GOT1 expressed in Escherichia coli BL21 (DE3) cells using aspartic acid and alpha-ketoglutaric acid as substrates incubated in presence of MDH1 and NADH
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human recombinant GOT1 using aspartic acid and alpha-ketoglutaric acid as substrates incubated in presence of MDH1 and NADH
Assay data:1 Active, 1 Tested
Inhibition of human recombinant GOT1 expressed in Escherichia coli BL21 star DE3 cells using aspartic acid and alpha-ketoglutaric acid as substrates incubated in presence of MDH1 and NADH
Reversible inhibition of GOT1 (unknown origin) at 10 fold IC50 preincubated for 30 mins followed by dilution to 0.5 fold IC50 and measured after 20 mins by dilution assay
Noncompetitive inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrate incubated in presence of pyridoxal 5'-phosphate
Noncompetitive inhibition of GOT1 (unknown origin) using alpha-Ketoglutaric acid as substrate assessed as inhibition constant by Michaelis-Menten equation based kinetic analysis
Noncompetitive inhibition of GOT1 (unknown origin) using aspartic acid as substrate assessed as inhibition constant by Michaelis-Menten equation based kinetic analysis
Noncompetitive inhibition of GOT1 (unknown origin) using alpha-Ketoglutaric acid as substrate assessed as reduction in Vmax with constant Km at 0 to 40 uM by Michaelis-Menten equation based kinetic analysis
Noncompetitive inhibition of GOT1 (unknown origin) using aspartic acid as substrate assessed as reduction in Vmax with constant Km at 0 to 40 uM by Michaelis-Menten equation based kinetic analysis
Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubated for 20 mins in presence of MDH1 and NADH by HTS assay
Assay data:6 Tested
Binding affinity to GOT1 (unknown origin) assessed as dissociation constant by microscale thermophoresis assay
Assay data:2 Active, 3 Tested
Aspartate transaminase assay (GOT1)
SummaryRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by GLOX enzyme-coupled fluorescence assay
Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay
Assay data:1 Active, 93 Tested
Inhibition of aspartate aminotransferase (unknown origin) at 4 mM using 5.55 mM L-aspartate as substrate
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on