Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Substrate activity at human OATP1B3 in CHO cells using 14C-labeled ligand
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of human OATP1B3
Substrate activity at OATP1B3 (unknown origin)
Inhibition of OATP1B3 (unknown origin)
SummaryPubMed CitationRelated BioAssays by Target
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In Vitro Uptake Transporter Assay from US Patent US9090657: "Compound and methods for its production"
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of OATP1B3 (unknown origin) expressed in HEK293 cells
Inhibition of human OATP1B3 assessed as reduction in intracellular probe substrate accumulation upto 100 uM by microplate scintillation counter analysis relative to control
Substrate activity at OATP1B3 (unknown origin) expressed in HEK293 cells assessed as ratio of drug uptake in absence of transporter inhibitor, estradiol-17beta-glucuronide to drug uptake in presence of transporter inhibitor, estradiol-17beta-glucuronide by LC-MS/MS analysis
Assay data:2 Tested
Inhibition of human OATP1B3 assessed as reduction in OATP1B3-mediated E217betaG transport at 14900 uM relative to control
Inhibition of OATP1B3 (unknown origin) at upto 3 uM
Inhibition of OATP1B3 (unknown origin) at 1 to 10 uM
Substrate activity at human OATP1B3 stably expressed in HEK293 cells assessed as ratio of total to passive cellular uptake at 1 uM incubated for 5 mins by LC/MS-MS analysis
Assay data:3 Tested
Substrate activity at human OATP1B3 stably expressed in HEK293 cells assessed as ratio of total to passive cellular uptake at 1 to 3 uM incubated for 0.5 to 4 mins by LC/MS-MS analysis
Inhibition of human OATP1B3 expressed in HEK293 cells n presence of rosuvastatin
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on