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Inhibition of MUC1 in human BT474 cells assessed as reduction in MUC1-C expression at 25 to 75 uM incubated for 3 days by immunoblot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of MUC1 in human MCF7 cells assessed as decrease in MUC1 protein level in whole cell lysates at 75 uM incubated for 3 days by immunoblot analysis
Assay data:1 Active, 2 Tested
Inhibition of MUC1 nuclear import in human MCF7 cells assessed as decrease in nuclear MUC1-C levels at 75 uM incubated for 3 days by immunoblot analysis
Inhibition of MUC1-CD dimerization in human MCF10A cells assessed as reduction in MUC1-C levels at 50 to 100 uM incubated for 3 days by immunoblot analysis
Inhibition of MUC1-CD dimerization (unknown origin) expressed in HEK293 cells assessed as disruption of interaction between Flag-MUC1-CD and GFP-MUC1-CD by coimmunoprecipitation assay
Inhibition of soluble unbound MUC1-CD dimerization (unknown origin) by immunoblot analysis
Assay data:2 Tested
SummaryRelated BioAssays by Target
Inhibition of biotinylated MUC1-CD dimerization (unknown origin) assessed as decrease in oligomer formation by streptavidin-HRP based assay relative to control
Assay data:1 Tested
Inhibition of biotinylated MUC1-CD dimerization (unknown origin) assessed as decrease in oligomer formation at 100 uM by streptavidin-HRP based assay relative to control
Assay data:9 Tested
Inhibition of MUC1 nuclear import in human MCF7 cells assessed as decrease in nuclear MUC1-C levels at 5 uM by Western blot analysis
Inhibition of MUC1 nuclear import in human ZR-75-1 cells assessed as decrease in nuclear MUC1-C levels at 5 uM by Western blot analysis
Binding affinity to His-tagged MUC1-CD (unknown origin) immobilized BIAcore sensor chip
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of MUC1-CD dimerization (unknown origin) expressed in HEK293 cells assessed as disruption of interaction between Flag-MUC1-CD and GFP-MUC1-CD at 5 mM by coimmunoprecipitation assay
Inhibition of His-tagged MUC1-CD dimerization (unknown origin) assessed as decrease in oligomer formation incubated for 1 hr by SDS-polyacrylamide electrophoresis method based luminescence assay
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
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