Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
NEK2 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of human recombinant Nek2 in presence of 150 uM ATP by ADP-Glo kinase assay
Inhibition of human recombinant Nek2 in presence of 50 uM ATP by ADP-Glo kinase assay
Assay data:13 Active, 18 Tested
Inhibition of NEK2 (unknown origin) at 100 nM relative to control
Assay data:2 Tested
Inhibition of human NEK2
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of NEK2 (unknown origin)
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Inhibition of NEK2 (unknown origin) at 1 uM relative to control
Assay data:43 Tested
Inhibition of NEK2 (unknown origin) at 10 uM relative to control
Assay data:10 Tested
Inhibition of NEK2 (unknown origin) assessed as dissociation constant
Assay data:8 Active, 5 Activity ≤ 1 µM, 8 Tested
Inhibition of human partial length wild type NEK2 expressed in bacterial system at 1 uM by KINOMEscan analysis relative to control
Selectivity interaction (Kinase panel (GlaxoSmithKline)) EUB0000603a NEK2
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Thermal Shift Assay. Domain: start/stop: M1-I271
Assay data:27 Tested
Inhibition of human full length recombinant NEK2 assessed as residual activity at 1 uM using poly(Glu, Tyr) 4:1 as substrate incubated for 40 mins in presence of [gamma 33P]-ATP by radiometric scintillation counting assay relative to control
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human full length recombinant NEK2 using ULight-p70 S6K peptide as substrate at 30 uM incubated for 30 mins by LANCE Ultra TR-FRET assay
Assay data:12 Tested
Inhibition of NEK2 (unknown origin) at 1 uM
NEK2 DiscoveRx kinase panel
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on