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In vitro inhibitory activity against [3H]GABA transport in rat cerebrocortical membranes in the presence of NNC-711 (100 uM); Phase 2
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
In vitro inhibitory activity against [3H]-GABA transport in rat cerebrocortical membranes in the presence of NNC-711 (100 uM); Phase 1
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
In vitro inhibitory activity against [3H]GABA transport in rat cerebrocortical membranes in the absence of NNC-711; Control
In vitro inhibitory activity against [3H]GABA transport in rat cerebrocortical membranes
Assay data:12 Tested
In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determined
Assay data:26 Active, 19 Activity ≤ 1 µM, 29 Tested
In vitro inhibition of rat neuronal (synaptosomal) GABA uptake.
Assay data:1 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of [3H]GABA uptake from rat brain membranes
Assay data:2 Tested
Percent inhibition of high affinity [3H]GABA uptake into rat brain synaptosomes at 100 uM
Assay data:1 Tested
Percent inhibition of high affinity [3H]GABA uptake into rat brain synaptosomes at 10 uM
Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane
Assay data:2 Active, 10 Tested
In vivo inhibition of GABA uptake in rat brain synaptic membranes
In vitro inhibition of GABA uptake in rat brain synaptic membranes
Assay data:1 Active, 5 Tested
In vivo maximal effect for synaptosomal GABA uptake at 100 uM
Assay data:6 Tested
Inhibition of [3H]GABA uptake in rat brain membranes
In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.
Assay data:1 Active, 6 Tested
In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain
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