Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Binding affinity to human CXCL12 assessed as dissociation constant incubated for 3 mins by surface plasmon resonance analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to human CXCL12 at 100 uM by glycan microarray analysis
Assay data:12 Tested
Tryptophan Fluorescence Assay from Article 10.1074/jbc.M803947200: "Small neutralizing molecules to inhibit actions of the chemokine CXCL12."
Assay data:4 Tested
Binding affinity to wild type CXCL12 (unknown origin) by NMR spectroscopy
Assay data:53 Tested
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes at 3 uM pre-incubated for 1 hr by FRET-based binding assay
Binding affinity to CXCL12 (unknown origin) assessed as inhibition of CXCL12 -induced increase in intracellular calcium level in EGFP-tagged CXCR4 expressing HEK cells at 10 uM
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes at 300 uM pre-incubated for 1 hr by FRET-based binding assay
Binding affinity to CXCL12 (unknown origin) assessed as changes in tryptophan fluorescence intensity
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes at 0.3 uM pre-incubated for 1 hr by FRET-based binding assay
Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes at 5 uM pre-incubated for 1 hr by FRET-based binding assay
Assay data:2 Tested
Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes at 1 uM pre-incubated for 1 hr by FRET-based binding assay
Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes at 10 uM pre-incubated for 1 hr by FRET-based binding assay
Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes at 30 uM pre-incubated for 1 hr by FRET-based binding assay
Binding affinity to Texas Red-labelled CXCL12 (unknown origin) assessed as inhibition of CXCL12-Texas Red binding to EGFP-labeled human CXCR4 expressed in HEK293 cell membranes pre-incubated for 1 hr by FRET-based binding assay
Assay data:29 Active, 23 Activity ≤ 1 µM, 47 Tested
Binding affinity to human [U-15N]CXCL12 L36C/A65C dimer mutant expressed in Escherichia coli assessed as induction of chemical shift perturbations at sY12 binding site by 2D 1H-15N SOFAST HMQC NMR spectroscopy
Binding affinity to human [U-15N]CXCL12 L36C/A65C dimer mutant expressed in Escherichia coli assessed as induction of chemical shift perturbations at Y61 residues by 2D 1H-15N SOFAST HMQC NMR spectroscopy
Binding affinity to human [U-15N]CXCL12 L36C/A65C dimer mutant expressed in Escherichia coli by 2D 1H-15N SOFAST HMQC NMR spectroscopy
Binding affinity to human [U-15N]CXCL12 L36C/A65C dimer mutant expressed in Escherichia coli assessed as induction of chemical shift perturbations at W57 residues by 2D 1H-15N SOFAST HMQC NMR spectroscopy
Binding affinity to human [U-15N]CXCL12 L36C/A65C dimer mutant expressed in Escherichia coli assessed as induction of chemical shift perturbations at C11/T31/Q37/V49 residues by 2D 1H-15N SOFAST HMQC NMR spectroscopy
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on