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Effect on human SOD1 protein homeostasis in ALS mouse model assessed as survival relative to control
Assay data:2 Tested
SummaryRelated BioAssays by Target
Inhibition of human erythrocyte CuZn-SOD by NBT dye based spectrophotometry
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human erythrocyte CuZn-SOD at 100 uM by NBT dye based spectrophotometry
Inhibition of human erythrocyte CuZn-SOD at 50 uM by NBT dye based spectrophotometry
Assay data:1 Tested
Inhibition of human erythrocytes CuZn-SOD by UV-VIS spectrophotometric method
Inhibition of human erythrocyte CuZn-SOD by UV-Visible spectrophotometric method
Inhibition of human erythrocyte CuZn-SOD
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of SOD1/SOD2 in human DLD1 cells at 100 uM using xanthine as substrate pretreated for 24 hrs followed by substrate addition measured after 5 mins by NBT dye based spectrophotometric method
Assay data:8 Active, 13 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Induction of superoxide dismutase activity in human erythrocytes at 100 ug/ml preincubated followed by AAPH addition measured after 2 hrs
Inhibition of human EGFP-tagged SOD1 A4V mRNA mutant induced endoplasmic reticulum stress expressed in mouse Neuro2a cells assessed as reduction in nuclear CHOP activation at 25 uM measured 72 hrs post transfection by Hoechst33342 staining-based epifluorescence microscopic analysis (Rvb = 35 to 37%)
Assay data:7 Tested
Binding affinity to human EGFP-tagged SOD1 A4V mutant mRNA expressed in mouse Neuro2a cells assessed as reduction in cells bearing inclusions at 25 uM measured 72 hrs post transfection by Hoechst33342 staining-based epifluorescence microscopic analysis (Rvb = 19 to 21%)
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Inhibition of CuZn-SOD in human erythrocytes
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Secondary Screen
Assay data:340 Active, 500 Tested
SummaryRelated BioAssays by Depositor
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
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