BioAssay by Target (List) for Gene (Select 699) - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

Items: 1 to 20 of 97

<< First< Prev

Page of 5

Select item 19405191.

Inhibition of Bub1 (unknown origin) by bio-chip based analysis

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Tested

AID:: 1940519

Summary Related BioAssays by Target

Select item 19151822.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000309b BUB1

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Tested

AID:: 1915182

Summary Related BioAssays by Target

Select item 19150993.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000540a BUB1

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Tested

AID:: 1915099

Summary Related BioAssays by Target

Select item 19149614.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000335a BUB1

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Tested

AID:: 1914961

Summary Related BioAssays by Target

Select item 18354245.

BUB1 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1835424

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18354226.

Abrogation of histone H2A-Thr120 phosphorylation

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1835422

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18354217.

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1835421

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18354208.

ePCA binding competition (equilibrium binding assay)

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1835420

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18354199.

BUB1 surface plasmon resonance (SPR) assay

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1835419

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 183541810.

BUB1 biochemical assay (high ATP)

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:2 Tested

AID:: 1835418

Summary Related BioAssays by Target

Select item 183541711.

BUB1 biochemical assay (low ATP)

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested

AID:: 1835417

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 180387212.

Kinase Assay from US Patent US10428063: "4H-pyrrolo[3,2-C]pyridin-4-one derivatives"

Source:: BindingDB

Protein Targets:: Mitotic checkpoint serine/threonine-protein kinase BUB1; ...
Total:: 1

Assay data:46 Active, 46 Activity ≤ 1 µM, 46 Tested

AID:: 1803872

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 180387113.

Kinase Assay from US Patent US10428044: "3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones"

Source:: BindingDB

Protein Targets:: Mitotic checkpoint serine/threonine-protein kinase BUB1; ...
Total:: 1

Assay data:466 Active, 404 Activity ≤ 1 µM, 480 Tested

AID:: 1803871

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179903714.

Bub1 Kinase Assay from US Patent US10308629: "1H-pyrrol-3-amines"

Source:: BindingDB

Protein Targets:: Mitotic checkpoint serine/threonine-protein kinase BUB1; ...
Total:: 1

Assay data:40 Active, 39 Activity ≤ 1 µM, 40 Tested

AID:: 1799037

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179840815.

Bub1 Kinase Assay from US Patent US10266548: "Substituted benzylindazoles for use as Bub1 kinase inhibitors in the treatment of hyperproliferative diseases"

Source:: BindingDB

Protein Targets:: Mitotic checkpoint serine/threonine-protein kinase BUB1; ...
Total:: 1

Assay data:183 Active, 159 Activity ≤ 1 µM, 187 Tested

AID:: 1798408

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179802216.

Bub1 kinase assay from US Patent US10227299: "3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones"

Source:: BindingDB

Protein Targets:: Mitotic checkpoint serine/threonine-protein kinase BUB1; ...
Total:: 1

Assay data:287 Active, 280 Activity ≤ 1 µM, 287 Tested

AID:: 1798022

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179718617.

Time-Resolved Fluorescence Energy Transfer (TR-FRET) Kinase Assay from US Patent US9765058: "Substituted benzylpyrazoles"

Source:: BindingDB

Protein Targets:: Mitotic checkpoint serine/threonine-protein kinase BUB1; ...
Total:: 1

Assay data:19 Active, 18 Activity ≤ 1 µM, 19 Tested

AID:: 1797186

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179494718.

Bub1 Kinase Assay from US Patent US9682995: "Amino-substituted isothiazoles"

Source:: BindingDB

Protein Targets:: Mitotic checkpoint serine/threonine-protein kinase BUB1; ...
Total:: 1

Assay data:6 Active, 1 Activity ≤ 1 µM, 121 Tested

AID:: 1794947

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 179398719.

KinomeScan assay: inhibition of BUB1

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:3 Active, 108 Tested

AID:: 1793987

Summary Compounds, Active Related BioAssays by Target

Select item 179360220.

Bub1(BUB1LGRL) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Mitotic checkpoint serine/threonine-protein kinase BUB1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793602

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

<< First< Prev

Page of 5

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (19)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (19)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (25)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (41)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (52)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (45)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (34)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (61)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Recent activity

Clear Turn Off Turn On

BioAssay by Target (List) for Gene (Select 699) (97)
PubChem BioAssay
Chromosome neighbors for GEO Profiles (Select 73998648) (20)
GEO Profiles

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay