Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Binding affinity to SUMO-conjugating UBC9 in human spontaneously immortalized CDH-/- MCF10A cell lysates assessed as change in melting temperature at 3.125 uM for 3 hrs by thermal proteome profiling assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Ubc9 in human A549 cells assessed as reduction in protein sumoylation by measuring Ubc9-Sumo adduct formation at 50 to 100 uM by Western blot analysis
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Substrate activity at Ubc9 (unknown origin) assessed as conversion to SUMO-1-compound adduct at 25 uM using SUMO-1 in presence of ATP by Western blotting method relative to DMSO control
Assay data:12 Tested
Substrate activity at Ubc9 (unknown origin) assessed as SUMO-1-compound adduct formation at 1 and 5 uM using SUMO-1 in presence of ATP by Western blotting method
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Ubc9 (unknown origin) assessed as reduction in fluorescent peptide FL-AR sumoylation using ATP, SUMO E1 and His-tagged SUMO-1 after 90 mins by competitive sumoylation microfluidic electrophoretic mobility shift biochemical assay
Assay data:3 Active, 7 Tested
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
Inhibition of purified SUMO E1/E2 (unknown origin)-mediated conjugation of His6-SUMO-1 to fluorescent peptide FL-AR at 30 uM after 90 mins by microfluidic electrophoretic mobility shift assay
Assay data:2 Active, 3 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Break-induced replication repair of damaged forks induces genomic duplications in human cells
Assay data:478 Active, 1380 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SAR analysis of the MOA of E2 SUMOylation inhibitors in an HTRF format
Assay data:50 Active, 1 Activity ≤ 1 µM, 54 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
SAR analysis of SUMOylation using HTRF in an in-Vitro dose response assay - Set 2
Assay data:16 Active, 31 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on