BioAssay by Target (List) for Gene (Select 84254) - PubChem BioAssay - NCBI

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Select item 19142701.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000167b CAMKK1

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1914270

Summary Related BioAssays by Target

Select item 19141802.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000169b CAMKK1

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1914180

Summary Related BioAssays by Target

Select item 18356853.

CAMKK1 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1835685

Summary Related BioAssays by Target

Select item 18348894.

CaMKK1(h) Kinase panel

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1834889

Summary Related BioAssays by Target

Select item 18340565.

Inhibition of CAMKK1 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1834056

Summary PubMed Citation Related BioAssays by Target

Select item 18162556.

Inhibition of human recombinant CAMKK1 assessed as reduction in substrate phosphorylation at 50 to 500 nM using ATP and Ulight-CKKSRGDYMTMQIG (IRS-1) incubated for 60 min by LANCE detection method

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1816255

Summary PubMed Citation Related BioAssays by Target

Select item 17939977.

KinomeScan assay: inhibition of CAMKK1

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:108 Tested

AID:: 1793997

Summary Related BioAssays by Target

Select item 17938728.

CAMKK1(CAK1LGT5) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793872

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 17926119.

CaMKK1(h) Eurofins kinase panel

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1792611

Summary Related BioAssays by Target

Select item 179221110.

CAMKK1 ProQinase selectivity panel

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1792211

Summary Related BioAssays by Target

Select item 179094411.

CAMKK1 (CAMKKA) Kinase screen

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1790944

Summary Related BioAssays by Target

Select item 179012312.

CAMKK1 Invitrogen selectivity data (BI)

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1790123

Summary Related BioAssays by Target

Select item 178920313.

CaMKK1(h) Eurofins Kinase panel

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1789203

Summary Related BioAssays by Target

Select item 178725614.

CaMKK1(h) Millipore kinase panel

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1787256

Summary Related BioAssays by Target

Select item 178633515.

CAMKK1 Invitrogen Lab (UK) kinase screen (BI)

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1786335

Summary Related BioAssays by Target

Select item 178590516.

CAMKK1 Kinase panel

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1785905

Summary Related BioAssays by Target

Select item 176840317.

Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to control

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:16 Active, 9 Activity ≤ 1 µM, 19 Tested

AID:: 1768403

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 176837918.

Inhibition of wild-type human partial length CAMKK1 (R65 to E414 residues) expressed in bacterial expression system assessed as residual binding at 1 uM by Kinomescan method relative to control

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:1 Tested

AID:: 1768379

Summary PubMed Citation Related BioAssays by Target

Select item 176835919.

Inhibition of wild-type human partial length CAMKK1 (R65 to E414 residues) expressed in bacterial expression system assessed as residual binding level at 1 uM by Kinomescan method relative to control

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:9 Tested

AID:: 1768359

Summary PubMed Citation Related BioAssays by Target

Select item 174932920.

Inhibition of CAMKK1 (unknown origin) assessed as residual activity measured at 1 uM

Source:: ChEMBL

Protein Target:: Calcium/calmodulin-dependent protein kinase kinase 1

Assay data:3 Tested

AID:: 1749329

Summary Related BioAssays by Target

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Target

Proteins (3)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (19)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (4)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (12)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (18)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (41)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (112)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (45)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (91)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (63)
BioAssays deposited by other experimentalists

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