BioAssay by Target (List) for Gene (Select 8805) - PubChem BioAssay - NCBI

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Select item 19186681.

Binding affinity to human TRIM24 bromodomain by BROMOscan method

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Active, 1 Tested

AID:: 1918668

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19148002.

Selectivity interaction (BromoScan panel) EUB0000205c TRIM24

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Active, 1 Tested

AID:: 1914800

Summary Compounds, Active Related BioAssays by Target

Select item 19126043.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1912604

Summary Related BioAssays by Target

Select item 19071384.

Inhibition of TRIM24 (unknown origin) measured alphascreen assay

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:21 Active, 2 Activity ≤ 1 µM, 39 Tested

AID:: 1907138

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19071375.

Inhibition of TRIM24 (unknown origin) at 20 uM measured alphascreen assay relative to control

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:39 Tested

AID:: 1907137

Summary PubMed Citation Related BioAssays by Target

Select item 19059626.

Binding affinity to TRIM24 (unknown origin) assessed as change in melting temperature at 100 uM incubated for 30 mins by thermal shift assay

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:5 Tested

AID:: 1905962

Summary PubMed Citation Related BioAssays by Target

Select item 18451257.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845125

Summary Related BioAssays by Target

Select item 18451248.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845124

Summary Related BioAssays by Target

Select item 18451239.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845123

Summary Related BioAssays by Target

Select item 184512210.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845122

Summary Related BioAssays by Target

Select item 184512111.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845121

Summary Related BioAssays by Target

Select item 184512012.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845120

Summary Related BioAssays by Target

Select item 184511913.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845119

Summary Related BioAssays by Target

Select item 184511814.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845118

Summary Related BioAssays by Target

Select item 184511715.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845117

Summary Related BioAssays by Target

Select item 184511616.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845116

Summary Related BioAssays by Target

Select item 184511517.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845115

Summary Related BioAssays by Target

Select item 184511418.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845114

Summary Related BioAssays by Target

Select item 184511319.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845113

Summary Related BioAssays by Target

Select item 184511220.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1845112

Summary Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (28)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (14)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (43)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (11)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (1,019)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (15)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (68)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (965)
BioAssays deposited by other experimentalists

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