Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of recombinant human Wnt3a in HEK293 cells assessed as Wnt signalling by measuring reduction in relative luminescence units incubated for 24 hrs by luciferase reporter assay
Assay data:11 Active, 11 Activity ≤ 1 µM, 11 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human Wnt3a in HEK293 cells assessed as Wnt signalling by measuring reduction in relative luminescence units at 10 uM incubated for 24 hrs by luciferase reporter assay relative to control
Assay data:1 Active, 18 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Evaluation of Biological Activity from US Patent US10457672: "γ-diketones as Wnt/β-catenin signaling pathway activators"
Assay data:101 Active, 1 Activity ≤ 1 nM, 93 Activity ≤ 1 µM, 128 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
WNT Pathway Reporter Gene Assay from US Patent US10285988: "Compounds for treatment of fibrosis diseases"
Assay data:30 Active, 2 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 30 Tested
Wnt-Luc Reporter Assay from US Patent US10251893: "N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as Wnt signaling modulators"
Assay data:227 Active, 107 Activity ≤ 1 nM, 226 Activity ≤ 1 µM, 227 Tested
HEK FOP Assay from US Patent US10130633: "Compounds"
Assay data:11 Active, 76 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
HEK TOP OncoFlash Assay from US Patent US10130633: "Compounds"
Assay data:76 Active, 72 Activity ≤ 1 µM, 76 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
HCT116 FOPFlash from US Patent US10130633: "Compounds"
Assay data:32 Active, 253 Tested
HCT116 TOPFlash Assay from US Patent US10130633: "Compounds"
Assay data:253 Active, 224 Activity ≤ 1 µM, 253 Tested
WNT pathway reporter gene assay from US Patent US10087181: "Compound as WNT signaling inhibitor, composition, and use thereof"
WNT Pathway Reporter Gene Assay from US Patent US9713612: "Compounds for treatment of cancer"
Luciferase Assay from US Patent US9682961: "Quinazoline derivative"
Assay data:26 Active, 23 Activity ≤ 1 µM, 26 Tested
Inhibition of Wnt3a in human SW480 cells assessed as LEF1 level at 30 uM incubated for 24 mins by quantitative real-time PCR analysis relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Wnt3a in human SW480 cells assessed as LEF1 level at 10 uM incubated for 24 mins by quantitative real-time PCR analysis relative to control
Inhibition of Wnt3a in human SW480 cells assessed as LEF1 level at 3.3 uM incubated for 24 mins by quantitative real-time PCR analysis relative to control
Inhibition of Wnt3a in human SW480 cells assessed as cyclin D1 level at 30 uM incubated for 24 mins by quantitative real-time PCR analysis relative to control
Inhibition of Wnt3a in human SW480 cells assessed as cyclin D1 level at 10 uM incubated for 24 mins by quantitative real-time PCR analysis relative to control
Inhibition of Wnt3a in human SW480 cells assessed as cyclin D1 level at 3.3 uM incubated for 24 mins by quantitative real-time PCR analysis relative to control
Inhibition of Wnt3a in human SW480 cells assessed as Axin2 level at 30 uM incubated for 24 mins by quantitative real-time PCR analysis relative to control
Inhibition of Wnt3a in human SW480 cells assessed as Axin2 level at 10 uM incubated for 24 mins by quantitative real-time PCR analysis relative to control
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on