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Counterscreen for molecules that bind rCAG RNA repeats: fluorescent based biochemical late stage dose response assay for inhibitors of the DNA-based (5'CAG/3'GTC) TO-PRO-1 dye complex (MedChem Round 1)
Assay data:4 Active, 31 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Fluorescence-based biochemical late stage dose response assay to identify molecules that bind r(CAG) RNA repeats (MedChem Round 1)
Assay data:6 Active, 31 Tested
Fluorescence-based biochemical late stage dose response assay to identify molecules that bind r(CAG) RNA repeats
Assay data:31 Active, 9 Activity ≤ 1 µM, 31 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Counterscreen for molecules that bind rCAG RNA repeats: fluorescent based biochemical late stage dose response assay for inhibitors of the DNA-based (5'CAG/3'GTC) TO-PRO-1 dye complex
Assay data:27 Active, 31 Tested
Counterscreen for molecules that bind rCAG RNA repeats: fluorescent based biochemical dose response assay for inhibitors of the DNA-based (5'CAG/3'GTC) TO-PRO-1 dye complex
Assay data:61 Active, 247 Tested
Fluorescence-based biochemical high throughput dose response assay to identify molecules that bind r(CAG) RNA repeats
Assay data:234 Active, 13 Activity ≤ 1 µM, 247 Tested
Summary of the probe development effort to identify molecules that bind r(CAG) RNA repeats
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Counterscreen for molecules that bind rCAG RNA repeats: fluorescent based biochemical counterscreen assay for inhibitors of the DNA-based (5'CAG/3'GTC) TO-PRO-1 dye complex
Assay data:4009 Active, 4257 Tested
Fluorescence-based biochemical high throughput confirmation assay to identify molecules that bind r(CAG) RNA repeats
Assay data:2969 Active, 4257 Tested
Fluorescence-based biochemical primary high throughput screening assay to identify molecules that bind r(CAG) RNA repeats
Assay data:4670 Active, 369245 Tested
Quantitative High-Throughput Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Summary
Assay data:11 Active, 11 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection confirmation (ATP)
Assay data:25 Active, 5 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 137 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS Assay Multiplex Screening to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection in HTT Q25 expressing cells (ATP)
Assay data:2 Active, 4 Activity ≤ 1 µM, 47 Tested
qHTS Assay Multiplex Screening to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (Protease relase)
Assay data:81 Active, 4 Activity ≤ 1 nM, 11 Activity ≤ 1 µM, 198 Tested
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP)
Assay data:2385 Active, 11 Activity ≤ 1 nM, 1603 Activity ≤ 1 µM, 221029 Tested
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytoprotection (ATP)
Assay data:307 Active, 227407 Tested
qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Cytotoxicity in HTT Striatal Cells
Assay data:2 Active, 5 Tested
Yeast cell-based screen for compounds that suppress polyglutamine aggregation in vivo (75Q-TubH)
Assay data:1040 Tested
SummaryPubMed Citation
Screen for compounds that induce the human heat shock transcriptional response (HSEluc)
Assay data:283 Tested
Protection from expanded polyglutamine huntingtin toxicity in PC12 cells
Assay data:69 Active, 1040 Tested
SummaryCompounds, Active
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