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DNAPK Enzyme Potency Assay (DNA-PK Enz) from US Patent US11884671: "Purinone compounds and their use in treating cancer"
Assay data:51 Active, 43 Activity ≤ 1 nM, 51 Activity ≤ 1 µM, 51 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
KRAS G12D LoEnz Biochemical Assay from US Patent US20240025919: "AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF"
Assay data:255 Active, 170 Activity ≤ 1 nM, 252 Activity ≤ 1 µM, 258 Tested
KRAS WT Biochemical Assay from US Patent US20240025919: "AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF"
Assay data:50 Active, 8 Activity ≤ 1 nM, 45 Activity ≤ 1 µM, 56 Tested
Inhibitory Activity of the Compounds of the Invention Against ROS1, NTRK and ALK and their Drug-Resistant Kinases from US Patent US20240025908: "COMPOUND USED AS KINASE INHIBITOR AND USE THEREOF"
Assay data:29 Active, 14 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 29 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
HTRF Assay from US Patent US20240018153: "BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF"
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
In Vitro Activity Against CBP from US Patent US20240016795: "BROMODOMAIN INHIBITORS FOR ANDROGEN RECEPTOR-DRIVEN CANCERS"
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Enzyme Activity Assay from US Patent US20240016777: "COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS"
Assay data:6 Active, 11 Tested
SummaryCompounds, Active
Enzyme-Linked Immunosorbent Assay ELISA from US Patent US11872217: "Indanes as PD-L1 inhibitors"
Assay data:49 Active, 37 Activity ≤ 1 µM, 49 Tested
TBD from US Patent US20240010642: "MODULATORS OF PROGRAMMED DEATH-LIGAND-1"
Assay data:7 Active, 2 Activity ≤ 1 µM, 18 Tested
Bioactivity Assay from US Patent US11866450: "Modulators of Cystic Fibrosis Transmembrane Conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulators"
Assay data:192 Active, 183 Activity ≤ 1 µM, 210 Tested
Enzyme-Linked Immunosorbent Assay-ELISA from US Patent US11866429: "Heteroaryl-biphenyl amines for the treatment of PD-L1 diseases"
Assay data:83 Active, 83 Activity ≤ 1 µM, 83 Tested
DYRK1A kinase assay from US Patent US20240002391: "4-ALKOXYPYRROLO[2,1-F][1,2,4]TRIAZINES AND PREPARATION AND USES THEREOF"
Assay data:421 Active, 56 Activity ≤ 1 nM, 419 Activity ≤ 1 µM, 421 Tested
Biochemical Assay from US Patent US20240002365: "PYRIDAZINE AND 1,2,4-TRIAZINE DERIVATIVES AS FGFR KINASE INHIBITORS"
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
p-Cl-ANS Fluorescent Binding Assay from US Patent US20240002339: "THERAPEUTIC COMPOUNDS AND METHODS"
Assay data:11 Active, 5 Activity ≤ 1 µM, 11 Tested
Surface Plasmon Resonance (SPR) from US Patent US20240002339: "THERAPEUTIC COMPOUNDS AND METHODS"
Assay data:20 Active, 7 Activity ≤ 1 µM, 29 Tested
Isothermal Titration Calorimetry (ITC) from US Patent US20240002339: "THERAPEUTIC COMPOUNDS AND METHODS"
Assay data:54 Active, 27 Activity ≤ 1 µM, 83 Tested
SARS-CoV-2 3C-like (3CL) Protease Fluorescence Assay (FRET) from US Patent US11858945: "Alkyne-containing antiviral agents"
Assay data:17 Active, 21 Activity ≤ 1 µM, 21 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Biological Assay from US Patent US11857552: "4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino]methyl]piperidin-3-ol compounds as CDK inhibitors"
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested
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