Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Selectivity interaction (AlphaScreen assay) EUB0000214b L3MBTL
Assay data:1 Active, 1 Tested
SummaryRelated BioAssays by Target
AlphaScreen Assay from Article 10.1021/cb500956g: "Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1."
Assay data:25 Tested
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Inhibition of L3MBTL1 (unknown origin) by fluorescence polarization assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of L3MBTL1 (unknown origin) by AlphaScreen assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of GST-fused L3MBTL1 3xMBT-D355N mutant (unknown origin)/biotinylated H4K20Me1 peptide interaction at 5 to 25 uM by pull down assay based western blot analysis
Assay data:2 Tested
Inhibition of GST-fused L3MBTL1 3xMBT domain (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells/biotinylated H4K20Me1 peptide interaction assessed as binding of L3MBT1 repeats to H4K20Me1 at 25 uM by pull-down assay based western blot analysis
Assay data:3 Tested
Inhibition of GST-fused L3MBTL1 3xMBT domain (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells/biotinylated H4K20Me1 peptide interaction assessed as binding of L3MBT1 repeats to H4K20Me1 at 5 uM by pull-down assay based western blot analysis
Inhibition of GST-fused L3MBTL1 3xMBT domain (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells/biotinylated H4K20Me1 peptide interaction assessed as binding of L3MBT1 repeats to H4K20Me1 at 1 uM by pull-down assay based western blot analysis
Inhibition of GST-fused L3MBTL1 3xMBT domain (unknown origin) expressed in Escherichia coli BL21 (DE3) pLysS cells/biotinylated H4K20Me1 peptide interaction assessed as binding of L3MBT1 repeats to H4K20Me1 by pull-down assay based western blot analysis
Antagonist activity at N-terminal His6-tagged L3MBTL1 (unknown origin) expressed in Escherichia coli BL21 Codon Plus RIL cells assessed as inhibition of L3MBTL1/biotinylated H4K20Me1 peptide interaction at 30 uM after 30 mins by AlphaScreen assay
Assay data:14 Tested
Antagonist activity at N-terminal His6-tagged L3MBTL1 (unknown origin) expressed in Escherichia coli BL21 Codon Plus RIL cells assessed as inhibition of L3MBTL1/biotinylated H4K20Me1 peptide interaction after 30 mins by AlphaScreen assay
Assay data:3 Active, 24 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Binding affinity to L3MBTL1 (unknown origin) by isothermal titration calorimetry
Assay data:2 Active, 4 Tested
Inhibition of His-tagged L3MBTL1 (unknown origin) using H4K20Me1 as substrate incubated for 30 mins at room temperature followed by incubation under dark condition for 30 mins by AlphaScreen assay
Assay data:2 Active, 25 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to L3MBTL1 (unknown origin) by isothermal titration calorimetric analysis
Assay data:1 Active, 4 Tested
Inhibition of L3MBTL1 (unknown origin) after 30 mins by AlphaScreen assay
Assay data:49 Active, 1 Activity ≤ 1 µM, 60 Tested
Binding affinity to L3MBTL1 (unknown origin) by isothermal titration calorimetric assay
Assay data:2 Active, 7 Tested
Displacement of FAM-AHA-ARTKQTARK(Me)STGGKA-CO2H from human L3MBTL1 assessed as apparent dissociation constant after 20 mins by FP-displacement Assay
Binding affinity to human L3MBTL1 by chemiluminescent assay
Assay data:1 Active, 2 Tested
Binding affinity to human L3MBTL1 by isothermal titration calorimetric assay relative to control
Binding affinity to human L3MBTL1 D355A mutant by isothermal titration calorimetric assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on