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Y2 (h) CEREP panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Y2/HU Eurofins SafetyScreen44 (BI)
Neuropeptide Y Y2 Eurofins-Panlabs radioligand binding assay
Assay data:12 Tested
PRESTO-Tango GPCRome screening (NPY2R)
Y2/HU Eurofins-Panlabs selectivity data (BI)
Y2 CEREP ligand profiling
Y2 receptor CEREP ligand profiling
Y2 (h) Ligand binding assay
Y2 (h) CEREP ligand profiling
hNPY2 Cerep panel
Y2 (h) Eurofins-Cerep binding assay
Displacement of [3H]UR-MK299 from human neuropeptide Y Y2 receptor expressed in CHO cells measured after 90 mins by scintillation counting analysis
Assay data:21 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human NPY2 at 0.1 to 1 uM
Allosteric antagonist activity at NPY2R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport at 30 uM by electrophysiology
Assay data:2 Tested
Allosteric antagonist activity at NPY2R in mouse descending colon mucosa assessed as reduction in rPP-induced ion transport at 0.3 to 30 uM by electrophysiology
Allosteric antagonist activity at eFYP-tagged human NPY2R expressed in COS7 cells co-expressing Gqi5-alpha assessed as inhibition of NPY-induced Ca2+ flux at 30 uM by Fluo-2 AM dye based fluorescent assay
Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation in presence of NPY2-R antagonist BITE0246 by FRET assay
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