Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Sodium Channel, Site 2 Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
NA+/SITE2/R Eurofins SafetyScreen44 (BI)
Inhibition of Nav1.4 (unknown origin) by whole-cell patch clamp assay
Assay data:2 Active, 7 Tested
Inhibition of human Nav1.4 expressed in HEK293 cells at -120 mV holding potential by automated patch clamp electrophysiology recording
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human Nav1.4 expressed in HEK293 cells by whole cell patch clamp electrophysiology recording
Assay data:10 Active, 10 Activity ≤ 1 µM, 22 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Effect on Nav1.4 (unknown origin) transfected in CHO cells assessed as activation of channel current in presence of 365 nm UV irradiation by whole-cell patch clamp electrophysiology
Assay data:2 Tested
Inhibition of full length human Nav1.4 expressed in HEK cells by whole cell voltage clamp analysis
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human Nav1.4 stably expressed in cells with train pulses to -20 mV at 0.1 Hz and holding potential of -95 mV by whole-cell Qube-automated patch clamp assay
Assay data:5 Active, 1 Activity ≤ 1 µM, 24 Tested
Voltage-Clamp Assay from US Patent US9675591: "Methods for treating seizure disorders and pain"
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Radioligand Binding Assay from US Patent US9694002: "Substituted benzamides and methods of use thereof"
Assay data:572 Active, 5 Activity ≤ 1 nM, 546 Activity ≤ 1 µM, 574 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Na+ channel (site 2) Eurofins-Cerep binding assay
Na+ channel (site 2) CEREP ligand profiling
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on