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Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry.
Assay data:1 Active, 239 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibitory activity (3 uM) against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assay; No inhibition
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assay
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Percentage inhibitory activity of compound against tyrosyl tRNA synthetase from mammalian cells was determined at 3 uM
Assay data:1 Tested
Inhibitory activity of compound against tyrosyl tRNA synthetase from mammalian cells was determined
Inhibitory activity (3 uM) against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assay
Inhibitory activity (3 uM) against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assay; NI = No inhibition
Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determined up to 3 uM; IA means Inactive
Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determined
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assay; NI = No inhibition
Assay data:5 Active, 1 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
Inhibitory activity against Bacterial Tyrosyl tRNA Synthetase
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 6 Tested
Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA Synthetase; NI=No inhibition
Assay data:3 Tested
Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA Synthetase
Assay data:7 Active, 3 Activity ≤ 1 µM, 8 Tested
Compound was tested for the inhibition of aminoacyl tRNA Synthetase
SummaryRelated BioAssays by Target
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