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Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000711a MAP3K20
Assay data:1 Tested
SummaryRelated BioAssays by Target
Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000132b MAP3K20
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000132b MAP3K20
Binding affinity to ZAK (unknown origin) assessed as percent of control at 100 nM by Kinomescan method relative to control
Assay data:29 Tested
SummaryPubMed CitationRelated BioAssays by Target
ZAK DiscoveRx kinase panel
ZAK(h) Kinase panel
Inhibition of ZAK (unknown origin) at 1 uM
Inhibition of ZAK (unknown origin) incubated for 1 hr by qPCR analysis
Assay data:3 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of ZAK (unknown origin) at 10 uM incubated for 1 hr by qPCR analysis
Assay data:1 Active, 1 Tested
Inhibition of human recombinant ZAK assessed as reduction in substrate phosphorylation at 500 nM using ATP and Ulight-CKKSRGDYMTMQIG (IRS-1) incubated for 60 min by LANCE detection method
KinomeScan assay: inhibition of ZAK
Assay data:108 Tested
ZAK(ZAK1LGY1) Takeda global kinase panel
Assay data:1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Target
ZAK(h) Eurofins kinase panel
ZAK ProQinase selectivity panel
NanoBRET (MAP3K20)
Assay data:2 Tested
ZAK Kinase screen
ZAK Invitrogen selectivity data (BI)
ZAK(h) Eurofins Kinase panel
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