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Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as unknown sterol content at 4 ug/ml measured after 48 hrs by GC-MS analysis
Assay data:4 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as eburicol content at 4 ug/ml measured after 48 hrs by GC-MS analysis (Rvb = 1.84%)
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as lanosterol content at 4 ug/ml measured after 48 hrs by GC-MS analysis
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as ergosterol content at 4 ug/ml measured after 48 hrs by GC-MS analysis (Rvb = 95.61%)
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as reduction in substrate consumption using lanosterol as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins by HPLC analysis
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as unknown sterol level at 0.0075 ug/ml measured after 18 hrs by GC-MS analysis (Rvb = 3.07 %)
Assay data:1 Tested
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as 14alpha-methylergosta-8,24(28)-dien-3beta-6alpha-diol level at 0.0075 ug/ml measured after 18 hrs by GC-MS analysis relative to control
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as eburicol level at 0.0075 ug/ml measured after 18 hrs by GC-MS analysis relative to control
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as ergosterol level at 0.0075 ug/ml measured after 18 hrs by GC-MS analysis (Rvb = 96.93 %)
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as lanosterol level at 0.0075 ug/ml measured after 18 hrs by GC-MS analysis relative to control
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as unknown sterol level at 0.25 ug/ml measured after 18 hrs by GC-MS analysis (Rvb = 3.07 %)
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as 14alpha-methylergosta-8,24(28)-dien-3beta-6alpha-diol level at 0.25 ug/ml measured after 18 hrs by GC-MS analysis relative to control
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as eburicol level at 0.25 ug/ml measured after 18 hrs by GC-MS analysis relative to control
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as ergosterol level at 0.25 ug/ml measured after 18 hrs by GC-MS analysis (Rvb = 96.93 %)
Inhibition of CYP51 in Candida albicans ATCC SC5314 assessed as lanosterol level at 0.25 ug/ml measured after 18 hrs by GC-MS analysis relative to control
Inhibition of CYP51 in Candida albicans SC5314 assessed as sterol level at 0.5 ug/ml measured after 12 hrs by GC-MS analysis (Rvb = 25.23%)
Inhibition of CYP51 in Candida albicans SC5314 assessed as sterol level at 4 ug/ml measured after 12 hrs by GC-MS analysis (Rvb = 25.23%)
Inhibition of CYP51 in Candida albicans SC5314 assessed as sterol level at 0.0625 ug/ml measured after 12 hrs by GC-MS analysis (Rvb = 25.23%)
Assay data:2 Tested
Inhibition of CYP51 in Candida albicans SC5314 assessed as eburicol level at 0.5 ug/ml measured after 12 hrs by GC-MS analysis (Rvb = 0.00%)
Inhibition of CYP51 in Candida albicans SC5314 assessed as eburicol level at 4 ug/ml measured after 12 hrs by GC-MS analysis (Rvb = 0.00%)
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