Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19593771.

Inhibition of human liver FBPase expressed in Escherichia coli BL21 (DE3) measured after 48 hrs by spectrophotometry analysis

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1959377

Summary Related BioAssays by Target

Select item 19593762.

Inhibition of recombinant C-terminal His-tagged human liver FBPase expressed in Escherichia coli BL21 (DE3)

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:5 Active, 1 Activity ≤ 1 µM, 5 Tested

AID:: 1959376

Summary Related BioAssays by Target

Select item 19593743.

Inhibition of human liver FBPase expressed in Escherichia coli

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 4 Tested

AID:: 1959374

Summary Related BioAssays by Target

Select item 19593734.

Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometry method

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1959373

Summary Related BioAssays by Target

Select item 19593725.

Inhibition of human liver FBPase

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:7 Active, 5 Activity ≤ 1 µM, 8 Tested

AID:: 1959372

Summary Related BioAssays by Target

Select item 19593706.

Inhibition of human liver FBPase by spectrophotometric method

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:10 Active, 7 Activity ≤ 1 µM, 13 Tested

AID:: 1959370

Summary Related BioAssays by Target

Select item 19410357.

Inhibition of FBPase in rat Primary hepatocyte assessed as reduction in glucose production

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Tested

AID:: 1941035

Summary Related BioAssays by Target

Select item 19410348.

Inhibition of FBPase in rat Primary hepatocyte assessed as reduction in glucose production at 160 uM

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Tested

AID:: 1941034

Summary Related BioAssays by Target

Select item 19410339.

Inhibition of FBPase (unknown origin)

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:4 Active, 4 Tested

AID:: 1941033

Summary Related BioAssays by Target

Select item 189312110.

Inhibition of human FBPase in ICR mouse serum starved primary hepatocytes assessed as glucose lowering effect at 50 to 100 uM

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Tested

AID:: 1893121

Summary PubMed Citation Related BioAssays by Target

Select item 189311911.

Inhibition of human FBPase in ICR mouse serum starved primary hepatocytes assessed as glucose lowering effect

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Active, 1 Tested

AID:: 1893119

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 189311112.

Binding affinity to ABPP-labeled FBPase (unknown origin) at 2 to 8 uM by silver staining based streptavidin blotting

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Active, 1 Tested

AID:: 1893111

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 189311013.

Binding affinity to ABPP-labeled FBPase (unknown origin) by silver staining based streptavidin blotting

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Tested

AID:: 1893110

Summary PubMed Citation Related BioAssays by Target

Select item 189310314.

Inhibition of human FBPase expressed Escherichia coli BL21 in by malachite green dye based spectrophotometry

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:7 Active, 9 Tested

AID:: 1893103

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 180231615.

Spectrophotometrical Assay from US Patent US9273021: "Dibenzofuran derivatives as inhibitors of fructose 1,6-bisphosphatase and methods of use thereof"

Source:: BindingDB

Protein Targets:: Fructose-1,6-bisphosphatase 1; ...
Total:: 2

Assay data:2 Active, 3 Tested

AID:: 1802316

Summary Compounds, Active Related BioAssays by Target

Select item 172409816.

Inhibition of human FBPase Y258A mutant

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1724098

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 172409617.

Inhibition of human FBPase R243A mutant

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Active, 1 Tested

AID:: 1724096

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 172409518.

Inhibition of human FBPase D127A mutant

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1724095

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 172409419.

Inhibition of human FBPase N125A mutant

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Tested

AID:: 1724094

Summary PubMed Citation Related BioAssays by Target

Select item 172409320.

Inhibition of human FBPase S124A mutant

Source:: ChEMBL

Protein Target:: Fructose-1,6-bisphosphatase 1

Assay data:1 Active, 1 Tested

AID:: 1724093

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Proteins (3)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (91)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (5)
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Activity (IC50, etc) ≤ 1 µM (61)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

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Literature Extraction (147)
BioAssays extracted from the literature

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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (147)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 1724098)
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Chromosome neighbors for GEO Profiles (Select 113311942) (20)
GEO Profiles
Homologene neighbors for GEO Profiles (Select 78026588) (0)
GEO Profiles
Age effect on normal adult brain: frontal cortical region
Age effect on normal adult brain: frontal cortical region
Accession: GDS5204

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Related DataSets for GEO Profiles (Select 117384145) (1)
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