Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19197411.

No assay from US Patent US11759530: "TKI permeability enhancers"

Source:: BindingDB

Protein Targets:: Activin receptor type-1B; ...
Total:: 22

Assay data:9 Active, 9 Activity ≤ 1 µM, 11 Tested

AID:: 1919741

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19195212.

Biochemical Assay (10 uM) from US Patent US11685719: "Pyridinone MK2 inhibitors and uses thereof"

Source:: BindingDB

Protein Targets:: Mitogen-activated protein kinase 1; ...
Total:: 2

Assay data:23 Active, 5 Activity ≤ 1 nM, 24 Activity ≤ 1 µM, 24 Tested

AID:: 1919521

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19195203.

Biochemical Assay (1 uM) from US Patent US11685719: "Pyridinone MK2 inhibitors and uses thereof"

Source:: BindingDB

Protein Targets:: MAP kinase-activated protein kinase 5; ...
Total:: 3

Assay data:23 Active, 2 Activity ≤ 1 µM, 24 Tested

AID:: 1919520

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19194554.

Enzyme-linked immunosorbent assay (ELISA) from US Patent US11655239: "Fused ring pyrimidine amino compound and preparation method, pharmaceutical composition, and use thereof"

Source:: BindingDB

Protein Targets:: ALK tyrosine kinase receptor; ...
Total:: 23

Assay data:32 Active, 18 Activity ≤ 1 nM, 32 Activity ≤ 1 µM, 32 Tested

AID:: 1919455

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19191375.

D3R2023 from Article : "Drug Design Data Resource Grand Challenge 3 Dataset: p38a"

Source:: BindingDB

Protein Targets:: Mitogen-activated protein kinase 14; ...
Total:: 1

Assay data:31 Active, 1 Activity ≤ 1 nM, 22 Activity ≤ 1 µM, 72 Tested

AID:: 1919137

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19151566.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000304b MAPK14

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Tested

AID:: 1915156

Summary Related BioAssays by Target

Select item 19150337.

Selectivity interaction (Leadprofiling screen (Ricerca, enzymes, receptors, transporters, and ion channels )) EUB0000347a MAPK14

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Tested

AID:: 1915033

Summary Related BioAssays by Target

Select item 19149138.

Selectivity interaction (MSD Pharma/Taiwan screen (enzymes and receptors) ) EUB0000296b MAPK14

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Tested

AID:: 1914913

Summary Related BioAssays by Target

Select item 19146259.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000746a MAPK12

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 12

Assay data:1 Tested

AID:: 1914625

Summary Related BioAssays by Target

Select item 191444410.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000263b MAPK12

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 12

Assay data:1 Tested

AID:: 1914444

Summary Related BioAssays by Target

Select item 191417811.

Selectivity interaction (Kinase panel (University of Dundee)) EUB0000169b MAPK13

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 13

Assay data:1 Tested

AID:: 1914178

Summary Related BioAssays by Target

Select item 191417712.

Selectivity interaction (Kinase panel (University of Dundee)) EUB0000169b MAPK12

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 12

Assay data:1 Tested

AID:: 1914177

Summary Related BioAssays by Target

Select item 191417613.

Selectivity interaction (Kinase panel (University of Dundee)) EUB0000169b MAPK11

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 11

Assay data:1 Tested

AID:: 1914176

Summary Related BioAssays by Target

Select item 191417514.

Selectivity interaction (Kinase panel (University of Dundee)) EUB0000169b MAPK14

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Tested

AID:: 1914175

Summary Related BioAssays by Target

Select item 191415315.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000718a MAPK12

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 12

Assay data:1 Tested

AID:: 1914153

Summary Related BioAssays by Target

Select item 191409116.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000713a MAPK14

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Tested

AID:: 1914091

Summary Related BioAssays by Target

Select item 191385917.

Selectivity interaction (Western Blot (inhibition of MAPK14 phosphorylation)) EUB0000132b MAPK14

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Tested

AID:: 1913859

Summary Related BioAssays by Target

Select item 191385818.

Selectivity interaction (Western Blot (inhibition of HSP27 phosphorylation at Ser82)) EUB0000132b MAPK14

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Tested

AID:: 1913858

Summary Related BioAssays by Target

Select item 191349619.

Selectivity interaction (Enzymatic assay) EUB0000624a MAPK14

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Tested

AID:: 1913496

Summary Related BioAssays by Target

Select item 191318820.

Affinity Biochemical interaction (ELISA (cell free)) EUB0000718a MAPK14

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 14

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913188

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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Target

Proteins (24)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (1,028)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (146)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (752)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (1,053)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

Assay Project (14)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (2,675)
BioAssays extracted from the literature
NIH MLP (15)
BioAssays deposited by the NIH Molecular Libraries Program
Other (190)
BioAssays deposited by other experimentalists

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