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CA Inhibition Assay from Article 10.1016/j.bmc.2009.05.002: "Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides."
Assay data:37 Active, 32 Activity ≤ 1 µM, 37 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant Candida albicans beta carbonic anhydrase NCE103 expressed in Escherichia coli preincubated for 15 mins by stopped-flow CO2 hydration assay
Assay data:24 Active, 24 Activity ≤ 1 µM, 24 Tested
Inhibition of recombinant full length Candida albicans NCE103 expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2 hydrase assay
Assay data:22 Active, 21 Activity ≤ 1 µM, 22 Tested
Inhibition of Candida albicans CaNce103 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method
Assay data:41 Active, 17 Activity ≤ 1 µM, 41 Tested
Inhibition of Candida albicans carbonic anhydrase preincubated for 15 mins at pH 8.3 by stopped flow CO2 hydration method
Assay data:5 Active, 1 Activity ≤ 1 µM, 5 Tested
Inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped flow CO2 hydration assay relative to phenol
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Candida albicans recombinant Nce103 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay
Assay data:26 Active, 17 Activity ≤ 1 µM, 27 Tested
Ratio of compound to acetazolamide activity for inhibition of Candida albicans recombinant Nce103
Assay data:1 Tested
inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assay
Assay data:32 Active, 31 Activity ≤ 1 µM, 32 Tested
Activation of Candida albicans beta-carbonic anhydrase Nce103 by stopped flow CO2 hydration assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 18 Tested
Activation of Candida albicans beta-carbonic anhydrase Nce103 assessed as enzyme catalytic rate at 10 uM by stopped flow CO2 hydration assay
Activity of Candida albicans beta-carbonic anhydrase Nce103 by stopped flow CO2 hydration assay
Inhibition of Candida albicans recombinant Nce103 by stopped-flow CO2 hydration assay
Assay data:37 Active, 15 Activity ≤ 1 µM, 37 Tested
Inhibition of Candida albicans recombinant Carbonic anhydrase pre-incubated for 15 mins by CO2 hydration stopped-flow assay
Assay data:8 Active, 2 Activity ≤ 1 µM, 17 Tested
Inhibition of Candida albicans Nce103
Assay data:1 Active, 14 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Candida albicans carbonic anhydrase overexpressed in Escherichia coli BL21 (DE3) by CO2 hydration stopped-flow assay
Assay data:4 Tested
Inhibition of Candida albicans Nce103 at 20 degC by CO2 hydration method
Assay data:1 Active, 1 Activity ≤ 1 µM, 5 Tested
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