Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of human placental aromatase using androstenedione as substrate incubated in dark for 16 hrs
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryRelated BioAssays by Target
Inhibition of human placental microsome aromatase using androstenedione as substrate assessed as reduction in 3H2O formation preincubated for 5 mins in presence of NADPH followed by microsomal protein addition and measured after 3 hrs
Assay data:4 Active, 2 Activity ≤ 1 µM, 4 Tested
Inhibition of recombinant human aromatase preincubated for 10 mins followed by substrate and beta-NADP+ addition and measured for 60 mins by fluorescence based assay
Assay data:10 Active, 8 Activity ≤ 1 µM, 10 Tested
Inhibition of human aromatase preincubated with NADPH regenerating system for 10 mins followed by substrate addition by fluorescence based analysis
Inhibition of aromatase in human placental microsomes using [1beta-3H]AD as substrate incubated for 20 mins in presence of NADPH
Assay data:275 Active, 181 Activity ≤ 1 µM, 393 Tested
Binding affinity to aromatase (unknown origin) assessed as inhibition constant
Assay data:2 Active, 2 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
Binding affinity to aromatase (unknown origin) assessed as change in gibbs free energy
Assay data:2 Tested
Inhibition of aromatase (unknown origin)
Assay data:128 Active, 56 Activity ≤ 1 µM, 138 Tested
Inhibition of aromatase in disrupted human MCF-7aro cells using [1beta-3H] androstenedione as substrate incubated for 1 hrs in the presence of NADPH
Assay data:1 Active, 1 Tested
Inhibition of aromatase in human MCF-7aro cells using [1beta-3H] androstenedione as substrate incubated for 1 hrs
Inhibition of aromatase in human MCF-7aro cells using [1beta-3H] androstenedione as substrate at 10 uM incubated for 1 hrs relative to control
Assay data:1 Tested
Potency index, ratio of test compound IC50 to Resveratrol IC50 for inhibition of Aromatase (unknown origin)
Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate preincubated for 10 mins followed by compound addition measured after 30 mins in presence of NADPH by HTS analysis
Inhibition of human Aromatase
Assay data:1 Active, 3 Tested
Inhibition of recombinant human aromatase
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of aromatase in human JEG-3 cells using Androst-4-ene-3,17-dione [1beta-3H] as substrate incubated for 1 hrs by scintillation counting analysis
Assay data:11 Active, 6 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 13 Tested
Inhibition of aromatase in human JEG-3 cells
Inhibition Assay from US Patent US11548860: "Pharmacophores, compounds and methods having application in the treatment of cancer through inhibition of CYP17A1 and CYP19A1"
Assay data:11 Active, 3 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human placental microsome CYP19 using [1beta-3H]-androstenedione as substrate
SummaryPubMed CitationRelated BioAssays by Target
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on