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Summary
Affinity Biochemical interaction (Microtiter-based biochemical assay) EUB0000737a ELANE
Assay data:1 Tested
SummaryRelated BioAssays by Target
Affinity Biochemical interaction (Microtiter-based biochemical assay) EUB0000735a ELANE
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Potency index, ratio of JO146 IC50 to test compound IC50 for inhibition of human neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pNA as substrate incubated for 10 mins
Assay data:17 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pNA as substrate incubated for 10 mins
Assay data:18 Active, 18 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of native full length human neutrophil elastase using N-succinyl-Ala-Ala-Pro-Val-pNA as substrate at 5 uM incubated for 30 mins followed by substrate addition by fluorescence based analysis
Inhibition of human neutrophil elastase using methoxysuccinyl-Ala-Ala-Pro-Val-pnitroanilide as substrate by spectrophotometric analysis
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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