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MARK3 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of MARK1 (unknown origin) by Ambit kinase assay
Inhibition of MARK2 (unknown origin) by Ambit kinase assay
Inhibition of MARK3 (unknown origin) by Ambit kinase assay
Binding affinity to recombinant MARK3 (unknown origin) assessed as dissociation constant by DSF assay
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of recombinant MARK3 (unknown origin) at 10 uM by DSF assay relative to staurosporine
Binding affinity to recombinant MARK3 (unknown origin) assessed as change in melting temperature at 10 uM by DSF assay
Inhibition of MARK3 (unknown origin) at 10 uM relative to control
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000315b MARK3
Selectivity interaction (KinomeScan (DiscoverX)) EUB0000262b MARK3
Thermal Shift Assay. Domain: start/stop: D48-R366
Assay data:27 Tested
Thermal Shift Assay. Domain: start/stop: M1-K331
Assay data:3 Tested
Inhibition of MARK1 (MARK) (unknown origin) at 1 uM relative to control
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of MARK2 (unknown origin) at 1 uM relative to control
Assay data:2 Tested
Inhibition of MARK3 (unknown origin) at 1 uM relative to control
MARK1 DiscoveRx kinase panel
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