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PIM3 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of PIM2 (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of PIM3 (unknown origin)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
No assay from US Patent US11759530: "TKI permeability enhancers"
Assay data:9 Active, 9 Activity ≤ 1 µM, 11 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Thermal Shift Assay. Domain: start/stop: M1-L326
Assay data:27 Tested
Binding affinity to human PIM3
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Binding affinity to human PIM2
Inhibition of His6-tagged full length human recombinant PIM3 expressed in Sf9 insect cells at 1 uM incubated for 60 mins in presence of [gamma33P]ATP by microplate scintillation counter relative to control
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of human PIM3 at 1 uM relative to control
Inhibition of human PIM2 at 1 uM relative to control
Inhibition of PIM-2 (unknown origin) at 1 uM
Inhibition of human PIM-2 at 2 uM by DiscoveryX Kinomescan assay relative to control
Inhibition of full-length human Pim-3 using RSRHSSYPAG as substrate incubated in presence of [gamma33P]ATP
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
PIM3 DiscoveRx kinase panel
PIM2 DiscoveRx kinase panel
Pim-3(h) Kinase panel
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