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Agonist activity at AhR in mouse Hepa2Dluc cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at AhR in AhR knockout human HT-29 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at AhR in human HT-29 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis
Assay data:3 Active, 3 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at AhR in human HT-29 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis
Agonist activity at AhR in human AZ-AHR reporter cell derived from human HepG2 cells assessed as increase in luciferase activity at 1 uM measured after 8 to 24 hrs
Assay data:1 Active, 3 Tested
Agonist activity at AhR in human AZ-AHR reporter cells derived from human HepG2 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 24 hrs by RT-PCR analysis
Agonist activity at AhR in human AZ-AHR reporter cells derived from human HepG2 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 24 hrs by RT-PCR analysis
Agonist activity at AhR in human LS180 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis
Agonist activity at AhR in human LS180 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis
Agonist activity at AhR in human AZ-AHR reporter cells derived from human HepG2 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis
Agonist activity at AhR in human LS180 cells assessed as binding of AhR to CYP1A1 promoter gene at 1 uM incubated for 90 mins by chromatin immunoprecipitation assay
Assay data:2 Active, 2 Tested
Agonist activity at AhR in human LS180 cell lysates assessed as induction of AhR-ARNT heterodimerization at 1 uM incubated for 90 mins by co-immunoprecipitation assay
Agonist activity at AhR in human LS180 cells assessed as induction of nuclear translocation at 1 uM incubated for 90 mins by DAPI staining based confocal fluorescence microscopic analysis
Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells assessed as relative efficacy incubated for 4 hrs by luciferase reporter gene assay relative to control
Assay data:12 Tested
Agonist activity at AhR (unknown origin) transfected in human AZ-AHR reporter cells derived from human HepG2 cells incubated for 4 hrs by luciferase reporter gene assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 11 Tested
Agonist activity at AhR in human LS180 cells assessed as induction of CYP1A1 mRNA expression at 1 uM incubated for 24 hrs by RT-PCR analysis
Agonist activity at AhR in human LS180 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 24 hrs by RT-PCR analysis
Agonist activity at AhR in human AZ-AHR reporter cells derived from human HepG2 cells assessed as induction of AHRR mRNA expression at 1 uM incubated for 4 hrs by RT-PCR analysis
Induction of Ahr signalling in human HaCaT cells assessed as upregulation of HRNR expression incubated for 48 hrs
Assay data:1 Active, 1 Tested
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