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Inhibitory Assay from US Patent US8865750: "Small molecule inhibitors of RGS proteins"
Assay data:1 Active, 1 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Rat regulator of G-protein signaling 4 (R4 family)
Assay data:2 Active, 2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Human regulator of G-protein signaling 4 (R4 family)
Assay data:10 Active, 10 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of RGS4 interaction with Galpha0 protein by flow cytometry protein interaction assay
Assay data:39 Active, 39 Activity ≤ 1 µM, 41 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of RGS4 GTPase accelrating activity
Assay data:1 Tested
Dose response-assay for SAR compounds that potentiate the regulator of G-protein signaling 4 (RGS4)
Assay data:13 Active, 13 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Counter screen dose-response assay for SAR compounds that potentiate the regulator of G-protein signaling 4 (RGS4) in non-induced RGS4 cells
Assay data:9 Active, 13 Tested
qHTS for Inhibitors of Regulator of G Protein Signaling(RGS) 4: Hit Validation
Assay data:19 Active, 27 Tested
Validation assay for identification of compounds that activate the regulator of G-protein signaling 4 (RGS4)
Assay data:1022 Active, 1147 Tested
Biochemical assay for compounds that inhibit RGS4 stimulation of Galpha1 nucleotide hydrolysis under receptor-independent steady-state conditions
Assay data:28 Active, 1 Activity ≤ 1 µM, 58 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Biochemical assay for compounds that inhibit AlF4- anion-dependent RGS4 binding to Galpha-o
Assay data:18 Active, 58 Tested
Inhibitors of Regulator of G Protein Signaling (RGS) 4: Summary
SummaryPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS
Assay data:152 Active, 301 Activity ≤ 1 µM, 390220 Tested
Second counter screen for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4): Non-induced cells with the primary screen assay without carbachol activation
Assay data:428 Active, 1925 Tested
Counter screen for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4): Non-induced cells with the primary screen assay
Assay data:386 Active, 1925 Tested
Validation assay for identification of compounds that inhibit the regulator of G-protein signaling 4 (RGS4)
Assay data:1078 Active, 1662 Tested
Summary of probe development for inhibitors of the regulator of G-protein signaling 4 (RGS4)
Summary of probe development for potentiators of the regulator of G-protein signaling 4 (RGS4)
Primary cell-based high-throughput screening assay for identification of compounds that inhibit regulator of G-protein signaling 4 (RGS4)
Assay data:1365 Active, 305679 Tested
Primary cell-based high-throughput screening assay for identification of compounds that potentiate/activate regulator of G-protein signaling 4 (RGS4)
Assay data:2824 Active, 305679 Tested
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