Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Displacement of 125I-liraglutide from GLP-1 (unknown origin) by competitive binding assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryRelated BioAssays by Target
Agonist activity at human N-terminal GLP-1 receptor
The Alizarin Assay (ARS) (Lactate) from US Patent US11767332: "Glucose-sensitive albumin-binding derivatives"
Assay data:36 Tested
SummaryRelated BioAssays by DepositorRelated BioAssays by Target
The Alizarin Assay (ARS) (Glucose) from US Patent US11767332: "Glucose-sensitive albumin-binding derivatives"
Assay data:43 Tested
Tag-Lite Binding Assay from US Patent US20230271949: "GLP-1R MODULATING COMPOUNDS"
Assay data:53 Active, 46 Activity ≤ 1 µM, 53 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Agonist activity at human GLP-1R expressed in HEK293 cells incubated for 30 mins and assessed as increase in cAMP accumulation measured by HTRF assay relative to control
Assay data:18 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at human GLP-1R expressed in HEK293 cells incubated for 30 mins and assessed as increase in cAMP accumulation measured by HTRF assay
Assay data:18 Active, 17 Activity ≤ 1 nM, 18 Activity ≤ 1 µM, 18 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
GPCR beta-arrestin recruitment assay with target: GLP1R Assay Type: PRESTO-Tango Concentration: 0.0000004
Assay data:211 Tested
GPCR beta-arrestin recruitment assay with target: GLP1R Assay Type: PRESTO-Tango Concentration: 0.000002
GPCR beta-arrestin recruitment assay with target: GLP1R Assay Type: PRESTO-Tango Concentration: 0.00001
Assay data:437 Tested
Agonist activity at FAP-tagged human GLP-1R expressed in HEK293 cells assessed as receptor internalization measured after 30 mins by nuclear staining based confocal microscopic analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at FAP-tagged human GLP-1R expressed in HEK293 cells assessed as receptor internalization preincubated for 30 mins followed by compound washout and measured after 2 hrs by nuclear staining based confocal microscopic analysis
Assay data:1 Tested
Displacement of [3H]PF-06883365 from FAP-tagged human GLP-1R expressed in CHO cells assessed as inhibition constant by radioligand binding assay
Assay data:4 Active, 1 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Displacement of [125I]GLP-1 from FAP-tagged human GLP-1R expressed in CHO cells assessed as inhibition constant by radioligand binding assay
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Agonist activity at FAP-tagged human GLP-1R expressed in HEK293 cells assessed as receptor internalization by measuring maximal efficacy relative to control
Assay data:3 Tested
Agonist activity at human GLP-1R expressed in PathHunter CHO-K1 GLP1R beta-arrestin-2 cell assessed as induction of beta-arrestin 2 recruitment by measuring maximum efficacy incubated for 90 mins by pathHunter assay relative to control
Assay data:4 Tested
Agonist activity at human GLP-1R expressed in PathHunter CHO-K1 GLP1R beta-arrestin-2 cell assessed as induction of beta-arrestin 2 recruitment incubated for 90 mins by pathHunter assay
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Agonist activity at human GLP-1R expressed in PathHunter CHO-K1 GLP1R beta-arrestin-1 cell assessed as induction of beta-arrestin 1 recruitment by measuring maximum efficacy incubated for 90 mins by pathHunter assay relative to control
Agonist activity at human GLP-1R expressed in PathHunter CHO-K1 GLP1R beta-arrestin-1 cell assessed as induction of beta-arrestin 1 recruitment incubated for 90 mins by pathHunter assay
Agonist activity at human GLP-1R expressed in PathHunter CHO-K1 GLP1R beta-arrestin-2 cells assessed as induction of beta-arrestin 2 recruitment by measuring maximum efficacy incubated for 90 mins in absence of BETP by PathHunter assay relative to control
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on