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Inhibition of SCD in human HepG2 cells
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of SCD in rat microsomes
Compound Profiling Methods from US Patent US10919885: "Compounds and uses thereof"
Assay data:161 Active, 77 Activity ≤ 1 µM, 463 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
SCD1 Enzymatic Assay from US Patent US9238658: "Substituted piperidinyl-carboxamide derivatives useful as SCD 1 inhibitors"
Assay data:41 Active, 43 Activity ≤ 1 µM, 44 Tested
Enzyme Activity Assay from US Patent US9168248: "Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase"
Assay data:26 Active, 8 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 26 Tested
Enzymatic Assay from US Patent US9102669: "Substituted piperidinyl-pyridazinyl derivatives useful as SCD 1 inhibitors"
Assay data:78 Active, 84 Activity ≤ 1 µM, 84 Tested
Enzyme Inhibition Assay from US Patent US8962837: "Nitrogen heterocycle derivatives, preparation thereof and application thereof in human therapeutics"
Assay data:24 Active, 24 Activity ≤ 1 µM, 24 Tested
Inhibition of SCD in CYP4F11 transfected human NCI-H1155 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Inhibition of SCD in empty vector transfected human NCI-H1155 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of SCD in human H1395 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of SCD in human HCC366 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Inhibition of SCD in human HCC417 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Inhibition of SCD in human H1993 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Inhibition of SCD in human H2073 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Inhibition of SCD in human HCC44 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of SCD in human H460 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Inhibition of SCD in human HCC95 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs in presence of oleate by cell titer Glo reagent based assay
Assay data:3 Tested
Inhibition of SCD in human NCI-H2122 cells expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs in presence of CYP4F inhibitor HET0016 by cell titer Glo reagent based assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Inhibition of SCD in human NCI-H1155 cells non-expressing CYP4F11 assessed as reduction in cell viability incubated for 96 hrs by cell titer Glo reagent based assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
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