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Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
Assay data:7220 Tested
Summary
SARS-CoV-2 3CL-Pro protease inhibition percentage at 20 M by FRET kind of response from peptide substrate
SummaryRelated BioAssays by Target
Inhibition of human ACE using MCA-RPPGFSAFK-Dnp-OH as substrate by fluorescence based analysis
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of human NEP using MCA-RPPGFSAFK-Dnp-OH as substrate by fluorescence based analysis
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human NEP expressed in insect cells preincubated for 1 hr using Cys(PT14)-Arg-Arg-Leu-Trp-OH as substrate and measured after 1 hr by fluorescence based assay
Assay data:31 Active, 3 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 31 Tested
Human Neutral endopeptidase (M13: Neprilysin)
Assay data:10 Active, 10 Tested
In vitro inhibition of rat neutral endopeptidase by using GAAP as substrate
Assay data:28 Active, 27 Activity ≤ 1 µM, 29 Tested
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