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Enzyme Inhibition Assay from Article 10.1016/j.bmcl.2006.01.017: "Discovery of novel heterocyclic factor VIIa inhibitors."
Assay data:9 Active, 5 Activity ≤ 1 µM, 12 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Selectivity for f7a over trypsin
Assay data:8 Tested
SummaryPubMed Citation
Selectivity for f7a over f2a
Selectivity for f7a over f10a
Binding affinity to trypsin
Assay data:1 Active, 1 Activity ≤ 1 µM, 5 Tested
Binding affinity to thrombin
Assay data:1 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to f10a
Assay data:3 Active, 2 Activity ≤ 1 µM, 5 Tested
Binding affinity to f7a
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
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