BioAssays for PubChem Compound (Select 59652086) - PubChem BioAssay - NCBI

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Select item 19142951.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000726a SIGMAR1

Source:: ChEMBL

Protein Target:: Sigma non-opioid intracellular receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914295

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19142942.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000726a SLC6A4

Source:: ChEMBL

Protein Target:: Sodium-dependent serotonin transporter

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914294

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19142933.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000726a HRH1

Source:: ChEMBL

Protein Target:: Histamine H1 receptor

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914293

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19142924.

Selectivity interaction (GPCR panel (PDSP screen)) EUB0000726a HTR2B

Source:: ChEMBL

Protein Target:: 5-hydroxytryptamine receptor 2B

Assay data:1 Active, 1 Tested

AID:: 1914292

Summary Compounds, Active Related BioAssays by Target

Select item 19132235.

Affinity Biochemical interaction (Enzyme inhibition assay) EUB0000726a MMP13

Source:: ChEMBL

Protein Target:: Collagenase 3

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913223

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18443996.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1 Tested

AID:: 1844399

Summary Related BioAssays by Target

Select item 18441977.

Thermal Shift Assay. Domain: start/stop: G861-E979

Source:: ChEMBL

Protein Target:: Transcription intermediary factor 1-alpha

Assay data:1502 Tested

AID:: 1844197

Summary Related BioAssays by Target

Select item 18434708.

Thermal Shift Assay. Domain: start/stop: E122-S403

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:1 Tested

AID:: 1843470

Summary Related BioAssays by Target

Select item 18432689.

Thermal Shift Assay. Domain: start/stop: E122-S403

Source:: ChEMBL

Protein Target:: Aurora kinase A

Assay data:1499 Tested

AID:: 1843268

Summary Related BioAssays by Target

Select item 184254110.

Thermal Shift Assay. Domain: start/stop: M1-S360

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 1

Assay data:1 Tested

AID:: 1842541

Summary Related BioAssays by Target

Select item 184233911.

Thermal Shift Assay. Domain: start/stop: M1-S360

Source:: ChEMBL

Protein Target:: Mitogen-activated protein kinase 1

Assay data:1499 Tested

AID:: 1842339

Summary Related BioAssays by Target

Select item 184161212.

Thermal Shift Assay. Domain: start/stop: M26-R383

Source:: ChEMBL

Protein Target:: Glycogen synthase kinase-3 beta

Assay data:1 Tested

AID:: 1841612

Summary Related BioAssays by Target

Select item 184141013.

Thermal Shift Assay. Domain: start/stop: M26-R383

Source:: ChEMBL

Protein Target:: Glycogen synthase kinase-3 beta

Assay data:1499 Tested

AID:: 1841410

Summary Related BioAssays by Target

Select item 184068314.

Thermal Shift Assay. Domain: start/stop: P449-E759

Source:: ChEMBL

Protein Target:: Fibroblast growth factor receptor 3

Assay data:1 Tested

AID:: 1840683

Summary Related BioAssays by Target

Select item 184048115.

Thermal Shift Assay. Domain: start/stop: P449-E759

Source:: ChEMBL

Protein Target:: Fibroblast growth factor receptor 3

Assay data:1499 Tested

AID:: 1840481

Summary Related BioAssays by Target

Select item 183975416.

Thermal Shift Assay. Domain: start/stop: M1-K294

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1 Tested

AID:: 1839754

Summary Related BioAssays by Target

Select item 183955217.

Thermal Shift Assay. Domain: start/stop: M1-K294

Source:: ChEMBL

Protein Target:: Casein kinase I isoform delta

Assay data:1499 Tested

AID:: 1839552

Summary Related BioAssays by Target

Select item 183882518.

Thermal Shift Assay. Domain: start/stop: M1-L298

Source:: ChEMBL

Protein Target:: Cyclin-dependent kinase 2

Assay data:1 Tested

AID:: 1838825

Summary Related BioAssays by Target

Select item 183862319.

Thermal Shift Assay. Domain: start/stop: M1-L298

Source:: ChEMBL

Protein Target:: Cyclin-dependent kinase 2

Assay data:1499 Tested

AID:: 1838623

Summary Related BioAssays by Target

Select item 183789620.

Thermal Shift Assay. Domain: start/stop: M626-G746

Source:: ChEMBL

Protein Target:: Peregrin

Assay data:1 Tested

AID:: 1837896

Summary Related BioAssays by Target

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Target

Proteins (2)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (37)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (42)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (52)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (4)
BioAssays extracted from the literature
Other (77)
BioAssays deposited by other experimentalists

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