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Enzyme Inhibition Assays (Assay 1) from US Patent US20230285340: "NEPRILYSIN INHIBITORS"
Assay data:52 Active, 26 Activity ≤ 1 nM, 52 Activity ≤ 1 µM, 52 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Neprilysin Inhibition Assay from US Patent US20230285340: "NEPRILYSIN INHIBITORS"
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Enzyme Inhibition Assay from US Patent US11547687: "Neprilysin inhibitors"
Assay data:59 Active, 25 Activity ≤ 1 nM, 59 Activity ≤ 1 µM, 59 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Enzyme NEP Inhibition Assay from US Patent US10123984: "Neprilysin inhibitors"
Assay data:47 Active, 21 Activity ≤ 1 nM, 47 Activity ≤ 1 µM, 47 Tested
Inhibition of human NEP using MCA-RPPGFSAFK-Dnp-OH as substrate by fluorescence based analysis
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human NEP expressed in insect cells preincubated for 1 hr using Cys(PT14)-Arg-Arg-Leu-Trp-OH as substrate and measured after 1 hr by fluorescence based assay
Assay data:31 Active, 3 Activity ≤ 1 nM, 26 Activity ≤ 1 µM, 31 Tested
Human Neutral endopeptidase (M13: Neprilysin)
Assay data:10 Active, 10 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
In vitro inhibition of rat neutral endopeptidase by using GAAP as substrate
Assay data:28 Active, 27 Activity ≤ 1 µM, 29 Tested
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