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Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay
Assay data:19 Active, 20 Activity ≤ 1 µM, 20 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay
Assay data:7 Active, 4 Activity ≤ 1 nM, 20 Activity ≤ 1 µM, 20 Tested
Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay
Assay data:19 Active, 3 Activity ≤ 1 nM, 20 Activity ≤ 1 µM, 20 Tested
Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 dye-based FLIPR assay
Assay data:11 Active, 4 Activity ≤ 1 nM, 20 Activity ≤ 1 µM, 20 Tested
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay
Assay data:43 Active, 4 Activity ≤ 1 nM, 34 Activity ≤ 1 µM, 43 Tested
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay
Assay data:43 Active, 6 Activity ≤ 1 nM, 31 Activity ≤ 1 µM, 43 Tested
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay
Assay data:43 Active, 7 Activity ≤ 1 nM, 36 Activity ≤ 1 µM, 43 Tested
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay
Assay data:34 Active, 4 Activity ≤ 1 nM, 18 Activity ≤ 1 µM, 43 Tested
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