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Agonist activity at PSGR/OR51E2 (unknown origin) expressed in human Hana3A cells co-transfected with CRE-Luc by luciferase reporter gene assay
Assay data:23 Active, 8 Activity ≤ 1 nM, 20 Activity ≤ 1 µM, 24 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Substrate activity at human ACE expressed in CHO cells by HPLC analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Mouse B1 receptor (Bradykinin receptors)
Assay data:10 Active, 10 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Rat B1 receptor (Bradykinin receptors)
Assay data:13 Active, 13 Tested
Mouse B2 receptor (Bradykinin receptors)
Assay data:12 Active, 12 Tested
Human B1 receptor (Bradykinin receptors)
Assay data:33 Active, 33 Tested
Human B2 receptor (Bradykinin receptors)
Assay data:23 Active, 23 Tested
Displacement of [3H]Bradykinin from human recombinant bradykinin B2 receptor expressed in CHEM1 cells after 60 mins
Antagonist activity at human recombinant bradykinin 2 receptor expressed in CHO cells assessed as inhibition of bradykinin-induced intracellular calcium mobilization
Assay data:2 Active, 2 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested
In vitro 50 % Maximal response in jugular vein expressing B2 receptor
Assay data:8 Active, 10 Activity ≤ 1 µM, 10 Tested
Binding affinity against rat Bradykinin receptor B2 expressed in CHO cells using [3H]-bradykinin as radioligand
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Ability to bind to human cloned B2 receptor in competition binding experiments with [3H]- bradykinin
Assay data:7 Active, 3 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested
Binding affinity towards human cloned Bradykinin receptor B2 expressed in CHO cells by [3H]bradykinin displacement.
Assay data:17 Active, 4 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 17 Tested
Binding affinity against human cloned Bradykinin receptor B2 expressed in CHO cells using [3H]-bradykinin as radioligand
Assay data:6 Active, 3 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
Binding affinity towards Bradykinin receptor B2 in human S34 clone cells
Assay data:13 Active, 6 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 13 Tested
Inhibitory activity against low affinity binding site of Bradykinin receptor in rat uterus membrane was reported.
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibitory activity against high affinity binding site of Bradykinin receptor in rat uterus membrane was reported.
Binding affinity towards bradykinin receptor using [3H]BK as radioligand in guinea pig ileum
Assay data:14 Active, 7 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 14 Tested
Inhibitory activity against low affinity binding site of Bradykinin receptor in guinea pig ileum
Assay data:9 Active, 1 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 9 Tested
Inhibitory activity against high affinity binding site of Bradykinin receptor in guinea pig ileum was reported.
Assay data:5 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested
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