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Stability in pH 7.5 Tris acetate/NaCl/DTT buffer after 20 mins in presence of Mg2+ by malachite green dye based assay
Assay data:7 Active, 7 Tested
SummaryCompounds, ActivePubMed Citation
Stability in pH 7.5 Tris acetate/NaCl/DTT buffer after 20 mins in presence of Mn2+ by malachite green dye based assay
Substrate activity at N-terminal His-tagged DIPP3-beta (unknown origin) expressed in Escherichia coli assessed as enzyme-mediated test compound metabolism after 20 mins in presence of Mn2+ by malachite green dye based assay
Assay data:2 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Substrate activity at N-terminal His-tagged DIPP3-alpha (unknown origin) expressed in Escherichia coli assessed as enzyme-mediated test compound metabolism after 20 mins in presence of Mn2+ by malachite green dye based assay
Substrate activity at N-terminal His-tagged DIPP2 (unknown origin) expressed in Escherichia coli assessed as enzyme-mediated test compound metabolism after 20 mins in presence of Mn2+ by malachite green dye based assay
Substrate activity at N-terminal His-tagged DIPP1 (unknown origin) expressed in Escherichia coli assessed as enzyme-mediated test compound metabolism after 20 mins in presence of Mn2+ by malachite green dye based assay
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Agonist activity at human GFP-tagged P2Y1R transfected in human 1321N1 cells assessed as induction of intracellular calcium mobilization by fluorescence assay
Assay data:14 Active, 11 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Activity against human P2Y2-GFP expressed in A549 cells by intracellular calcium increase
Assay data:5 Active, 1 Activity ≤ 1 µM, 7 Tested
Ability to inhibit the rat muscle adenylate kinase lII in competition with the AMP varied
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Ability to inhibit the rat muscle adenylate kinase (AK II) isozyme in competition with the ATP varied
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Ability to inhibit the rat muscle adenylate kinase (AK II) isozyme in competition with the AMP varied
Ability to inhibit the rat muscle adenylate kinase isozyme in competition with the ATP varied
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Ability to inhibit the rat muscle adenylate kinase isozyme in competition with the AMP varied
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
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