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Inhibition of DNA dependent ATPase activity of flag-tagged recombinant DNA2 D294A mutant (unknown origin) expressed in 293T cells using flap DNA substrate
Assay data:5 Active, 38 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of nuclease activity of flag-tagged recombinant DNA2 (unknown origin) expressed in 293T cells at 250 uM using [32P]-labeled flap DNA substrate incubated for 15 mins by denaturing PAGE method
Agonist activity at P2Y2 receptor H184A mutant (unknown origin) expressed in human 1321N1 astrocytoma cells assessed as increase in intracellular calcium mobilization after 1 hr by Fluo-4 AM dye based fluorescence assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at P2Y2 receptor Y288F mutant (unknown origin) expressed in human 1321N1 astrocytoma cells assessed as increase in intracellular calcium mobilization after 1 hr by Fluo-4 AM dye based fluorescence assay
Agonist activity at wild type P2Y2 receptor (unknown origin) expressed in human 1321N1 astrocytoma cells assessed as increase in intracellular calcium mobilization after 1 hr by Fluo-4 AM dye based fluorescence assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Agonist activity at P2Y2 receptor S193A mutant (unknown origin) expressed in human 1321N1 astrocytoma cells assessed as increase in intracellular calcium mobilization after 1 hr by Fluo-4 AM dye based fluorescence assay
Agonist activity at P2Y2 receptor Y114F mutant (unknown origin) expressed in human 1321N1 astrocytoma cells assessed as increase in intracellular calcium mobilization after 1 hr by Fluo-4 AM dye based fluorescence assay
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at P2Y2 receptor F261A mutant (unknown origin) expressed in human 1321N1 astrocytoma cells assessed as increase in intracellular calcium mobilization after 1 hr by Fluo-4 AM dye based fluorescence assay
Agonist activity at P2Y2 receptor R194A mutant (unknown origin) expressed in human 1321N1 astrocytoma cells assessed as increase in intracellular calcium mobilization after 1 hr by Fluo-4 AM dye based fluorescence assay
SummaryCompounds, ActivePubMed Citation
Agonist activity at human P2Y2 receptor expressed in 1321N1 cells assessed as [3H]-inositol phosphate accumulation measured after 90 mins by anion exchange chromatographic method
Assay data:10 Active, 9 Activity ≤ 1 µM, 16 Tested
Agonist activity at P2Y2 receptor in BEA cells (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Agonist activity at P2Y2 receptor in human CF/T43 cells
Agonist activity at P2Y2 receptor in NG108-15 cells (unknown origin)
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Agonist activity at P2Y2 receptor (unknown origin) assessed as reduction in inositol phosphate accumulation
Human P2Y2 receptor (P2Y receptors)
Assay data:17 Active, 17 Tested
Human P2Y6 receptor (P2Y receptors)
Assay data:19 Active, 19 Tested
Human P2Y4 receptor (P2Y receptors)
Assay data:12 Active, 12 Tested
Human P2Y11 receptor (P2Y receptors)
Assay data:15 Active, 15 Tested
Rat P2Y4 receptor (P2Y receptors)
Assay data:7 Active, 7 Tested
Activity of Bacillus subtilis N-terminal His-tagged ANT(6) expressed in Escherichia coli BL21(DE3) cells assessed as adenylated product by Michaelis-Menten kinetics
Assay data:4 Active, 12 Tested
SummaryCompounds, Active
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