Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Compound was evaluated for inhibition of human PDE4D in an in vitro cell free assay measured by scintillation proximity assay
Assay data:109 Active, 1 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 1242 Tested
SummaryRelated BioAssays by Target
Anticancer activity against mouse L1210 cells
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Summary
Anticancer activity against human K562 cells
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Anticancer activity against human CCRF-CEM cells
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Anticancer activity against human HEp-2 cells
Inhibition of Ribonucleotide reductase (unknown origin)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Primary qHTS for Inhibitors of ATXN expression
Assay data:2593 Active, 3 Activity ≤ 1 nM, 2671 Activity ≤ 1 µM, 361713 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) in an RCH-ACV wild type WT cells (2C)
Assay data:2970 Active, 9 Activity ≤ 1 nM, 1016 Activity ≤ 1 µM, 10037 Tested
Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) in an isogenic RCH-ACV NSD2 p.E1099K mutant (9B)
Assay data:2826 Active, 4 Activity ≤ 1 nM, 946 Activity ≤ 1 µM, 10037 Tested
Cytotoxicity against human HL60 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Cytotoxicity against human RL cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human Granta cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human CCRF-CEM cells assessed as decrease in cell viability after 72 hrs by MTT assay
Human pregnane X receptor (PXR) activation by small molecules, qHTS assay
Assay data:229 Active, 16 Activity ≤ 1 µM, 2454 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
CYP3A4 induction through human pregnane X receptor (PXR) by small molecules, qHTS assay
Assay data:172 Active, 50 Activity ≤ 1 µM, 2454 Tested
Human pregnane X receptor (PXR) small molecule agonists, qHTS assay
Assay data:2218 Active, 1 Activity ≤ 1 nM, 106 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
Drug repurposing screens with cells derived from glioblastoma tumor samples
Assay data:1237 Active, 3 Activity ≤ 1 nM, 360 Activity ≤ 1 µM, 3733 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approved drugs and bioactive compounds
Assay data:1106 Active, 14 Activity ≤ 1 nM, 6478 Activity ≤ 1 µM, 7578 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
qHTS assay to identify small molecule antagonists of the sonic hedgehog signaling (Shh) pathway: Summary
Assay data:1156 Active, 2 Activity ≤ 1 nM, 322 Activity ≤ 1 µM, 9667 Tested
qHTS assay to identify small molecule antagonists of the sonic hedgehog signaling (Shh) pathway
Assay data:1356 Active, 2 Activity ≤ 1 nM, 487 Activity ≤ 1 µM, 9667 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on