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Inhibition of human NEP using MCA-RPPGFSAFK-Dnp-OH as substrate by fluorescence based analysis
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant human Neprilysin using Suc-Ala-Ala-Phe-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluorometry
Assay data:2 Active, 2 Activity ≤ 1 µM, 3 Tested
Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetry
Assay data:12 Active, 1 Activity ≤ 1 nM, 12 Activity ≤ 1 µM, 12 Tested
Inhibition of neutral endopeptidase (NEP).
Assay data:15 Active, 6 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Compound was tested for inhibition of rat kidney neutral endopeptidase
Assay data:4 Active, 5 Activity ≤ 1 µM, 5 Tested
Tested for binding affinity against neutral endopeptidase (NEP)
Tested for inhibition against neutral endopeptidase (NEP)
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Compound was evaluated for inhibition of recombinant human neprilysin(NEP).
Assay data:6 Active, 7 Activity ≤ 1 µM, 7 Tested
Inhibitory activity against Endopeptidase
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Concentration for 50% inhibition of activity of rat kidney enkephalinase
Assay data:10 Active, 5 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 10 Tested
Inhibitory activity against angiotensin I converting enzyme (ACE)
Assay data:14 Active, 3 Activity ≤ 1 nM, 14 Activity ≤ 1 µM, 15 Tested
Inhibitory activity against angiotensin-converting enzyme (ACE).
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