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Agonist activity at recombinant human GPR18 expressed in HEK293 cells assessed as induction of p44/42 MAPK phosphorylation after 5 mins by Western blot analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at recombinant full length human GPR18 expressed in CHO cells assessed as forskolin-stimulated cAMP accumulation after 10 mins by enzyme immunoassay
Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approved drugs and bioactive compounds
Assay data:1106 Active, 14 Activity ≤ 1 nM, 6478 Activity ≤ 1 µM, 7578 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen2, ratio channel
Assay data:637 Active, 202 Activity ≤ 1 µM, 2566 Tested
qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen 2, green channel
Assay data:399 Activity ≤ 1 µM, 2566 Tested
SummaryCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 ratio channel
Assay data:502 Active, 187 Activity ≤ 1 µM, 2552 Tested
qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green channel
Assay data:2 Active, 385 Activity ≤ 1 µM, 2552 Tested
qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway
Assay data:146 Active, 1 Activity ≤ 1 nM, 175 Activity ≤ 1 µM, 9305 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway
Assay data:233 Active, 2 Activity ≤ 1 nM, 236 Activity ≤ 1 µM, 10486 Tested
qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen
Assay data:583 Active, 15 Activity ≤ 1 nM, 316 Activity ≤ 1 µM, 10486 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary
Assay data:1260 Active, 187 Activity ≤ 1 µM, 10486 Tested
qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Assay data:746 Active, 26 Activity ≤ 1 nM, 525 Activity ≤ 1 µM, 18112 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
qHTS for Inhibitors of Glutaminase (GLS): LOPAC Validation
Assay data:105 Active, 69 Activity ≤ 1 µM, 1280 Tested
qHTS for Inhibitors of Polymerase Eta
Assay data:4746 Active, 220 Activity ≤ 1 µM, 392343 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
qHTS for inhibitors of binding or entry into cells for Marburg Virus
Assay data:5375 Active, 30 Activity ≤ 1 nM, 10501 Activity ≤ 1 µM, 301745 Tested
Assay data:3699 Active, 99 Activity ≤ 1 nM, 6304 Activity ≤ 1 µM, 300904 Tested
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